Santhoshkumar Bandegudda, Kvv N Raju, Suseela Kodandapani, Jayakartik Rao
{"title":"Primary osteosarcoma of breast - A clinical camouflage: Case report.","authors":"Santhoshkumar Bandegudda, Kvv N Raju, Suseela Kodandapani, Jayakartik Rao","doi":"10.4103/jcrt.jcrt_1689_21","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Primary sarcoma of the breast is a rare clinical entity with an incidence of less than 1% among cases of breast cancer. Primary osteosarcoma of the breast is a very rare disease that shares clinical features similar to metaplastic breast carcinoma. A 57-year-old female Dravidian patient presented with a breast lump. A needle biopsy was suggestive of carcinoma. However, the mammogram was suggestive of dense calcification lesion, which is unusual in carcinoma. She underwent breast conservation surgery with sentinel lymph node biopsy; final histopathology was suggestive of osteosarcoma of the breast. After a follow-up of 18 months, the patient is healthy and disease-free. Primary breast osteosarcoma has to be considered as one of the differential diagnoses to metaplastic carcinoma and warrants a different treatment approach. Whenever there is discordance in clinical features, imaging, and histology, thorough evaluation with the mammogram, immunohistochemistry, and PET scan helps to resolve the issue.</p>","PeriodicalId":15208,"journal":{"name":"Journal of cancer research and therapeutics","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer research and therapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/jcrt.jcrt_1689_21","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/7/15 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Primary sarcoma of the breast is a rare clinical entity with an incidence of less than 1% among cases of breast cancer. Primary osteosarcoma of the breast is a very rare disease that shares clinical features similar to metaplastic breast carcinoma. A 57-year-old female Dravidian patient presented with a breast lump. A needle biopsy was suggestive of carcinoma. However, the mammogram was suggestive of dense calcification lesion, which is unusual in carcinoma. She underwent breast conservation surgery with sentinel lymph node biopsy; final histopathology was suggestive of osteosarcoma of the breast. After a follow-up of 18 months, the patient is healthy and disease-free. Primary breast osteosarcoma has to be considered as one of the differential diagnoses to metaplastic carcinoma and warrants a different treatment approach. Whenever there is discordance in clinical features, imaging, and histology, thorough evaluation with the mammogram, immunohistochemistry, and PET scan helps to resolve the issue.
摘要：乳腺原发性肉瘤是一种罕见的临床实体，发病率不到乳腺癌病例的 1%。乳腺原发性骨肉瘤是一种非常罕见的疾病，其临床特征与移行细胞乳腺癌相似。一名 57 岁的德拉维德族女性患者因乳房肿块就诊。针刺活检提示为癌。然而，乳房 X 光检查提示为致密钙化病变，这在癌症中并不常见。她接受了乳房保护手术，并进行了前哨淋巴结活检；最终组织病理学检查提示为乳房骨肉瘤。经过 18 个月的随访，患者健康无病。原发性乳腺骨肉瘤必须被视为移行细胞癌的鉴别诊断之一，并需要采取不同的治疗方法。每当临床特征、影像学和组织学出现不一致时，通过乳房 X 线照片、免疫组化和正电子发射计算机断层扫描进行全面评估有助于解决问题。
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The journal will cover technical and clinical studies related to health, ethical and social issues in field of Medical oncology, radiation oncology, medical imaging, radiation protection, non-ionising radiation, radiobiology. Articles with clinical interest and implications will be given preference.
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