Association of Age with the Expression of Denervation Marker in the Neuromuscular Junction of Male Wistar Rats

Abstract

Methods: In this study, 7 young adult male rats of 4 to 6 months of age and 7 old male rats of 24 to 26 months of age, were tested. after a twoweek familiarization period, the soleus and plantaris muscles of the rats were removed, embedded, and subjected to immunohistochemically staining to determine the neuromuscular junction site and neural cell adhesion molecule (NCAM) expression rate. The results were analyzed by analysis of variance at the significant level of p ≤ 0.01.