Evaluation of in vitro anti-inflammatory activity of the spadix of Colocasia affinis

科技视界 Pub Date : 2019-06-30 DOI:10.33493/SCIVIS.19.02.06

Vanlalhruaii, C. Malsawmtluangi, H. Lalhlenmawia

引用次数: 2

Abstract

The methanolic extract of C. affinis was evaluated for its in-vitro anti-inflammatory activity by bovine serum albumin denaturation method, egg albumin denaturation method and protease inhibition method at different concentrations. Diclofenac sodium was used as the reference drug. The extract exhibits anti-inflammatory activity in a concentration-dependent manner. In bovine serum albumin denaturation method, the extract at concentrations of 100, 200, 400, 600, 800, 1000 µg/ml showed 25.49, 28.43, 31.37, 37.25, 41.17, 48.03% inhibition respectively. In egg albumin denaturation method, the concentrations of 50, 100, 200, 300, 400, 500 µg/ml showed 5.3, 9.89, 28.12, 32.8, 43.2, 52.8% inhibition respectively. In protease inhibition method the extract at concentration of 100, 200, 300, 400, 500 µg/ml showed 8.87, 19.32, 28.56, 43.96, 59.92% inhibition respectively. Therefore, from the results it can be concluded that the methanolic extract of C. affinis possesses anti-inflammatory activity.

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附着物叶柄体外抗炎活性评价

采用牛血清白蛋白变性法、鸡蛋白蛋白变性法和不同浓度的蛋白酶抑制法对仿金针叶甲醇提取物进行体外抗炎活性评价。以双氯芬酸钠为对照药。提取物具有浓度依赖性的抗炎活性。在牛血清白蛋白变性法中，100、200、400、600、800、1000µg/ml提取物的抑制率分别为25.49%、28.43、31.37、37.25、41.17、48.03%。在鸡蛋白蛋白变性法中，50、100、200、300、400、500µg/ml的抑制率分别为5.3、9.89、28.12、32.8、43.2、52.8%。在蛋白酶抑制法中，100、200、300、400、500µg/ml提取物的抑制率分别为8.87%、19.32%、28.56%、43.96%、59.92%。由此可见，附着物甲醇提取物具有抗炎活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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