Hemangioblastomas of the cauda equina: Clinical features and long-term surgical outcomes

IF 1.5 4区医学 Q4 CLINICAL NEUROLOGY

Neurochirurgie Pub Date : 2023-11-04 DOI:10.1016/j.neuchi.2023.101513

Bo Han , Liang Zhang , Wenqing Jia

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引用次数: 0

Abstract

Background

Spinal hemangioblastomas (HBs) that involving cauda equina are rare. Data on clinical characteristics and long-term intervention outcomes of patients harboring cauda equina HBs remain lacking due to its scarcity.

Objective

This study aims to present the clinical-radiological features and treatment results of this rare pathology by using cases from a single center.

Methods

A review of demographic data and intervention outcomes of patients harboring cauda equina HBs in our department between 2009 and 2020 was retrospectively carried out.

Results

Ten consecutive adult patients were incorporated, with a slight female predominance (n = 6, 60%). The mean age was 39.9 ± 14.7 (range: 18–58) years. Six patients (60%) had von Hippel‒Lindau (VHL) syndrome and showed multiple symptoms and severe neurological deficits, while 4 (40%) were in the sporadic group and only presented pain symptoms. During follow-up, 3 patients (30%) experienced lesion relapse and underwent repeated surgery. Favorable outcomes were achieved in all patients.

Conclusion

Cauda equina HBs are rare spinal vascular lesions that should be differentiated from other lumbar canal lesions. Total surgical resection is the main treatment modality and can benefit patients, even recurrent patients. The treatment outcome is usually satisfactory, especially in sporadic cases.

查看原文本刊更多论文

马尾血管母细胞瘤：临床特征和长期手术结果。

背景：累及马尾神经的脊髓血管母细胞瘤是罕见的。由于缺乏关于携带马尾HBs的患者的临床特征和长期干预结果的数据，因此仍然缺乏。目的：本研究旨在通过单个中心的病例介绍这种罕见病理的临床放射学特征和治疗结果。方法：回顾性分析2009年至2020年我科携带马尾HBs患者的人口学数据和干预结果。结果：连续10例成年患者被纳入，其中女性略占优势（n = 60%）。平均年龄39.9岁 ± 14.7（范围：18-58）岁。6名患者（60%）患有von Hippel-Lindau（VHL）综合征，表现出多种症状和严重的神经功能缺损，而4名患者（40%）属于散发组，仅表现出疼痛症状。在随访期间，3名患者（30%）出现病变复发并接受了反复手术。所有患者都取得了良好的结果。结论：马尾HBs是一种罕见的脊髓血管病变，应与其他椎管病变鉴别。全手术切除是主要的治疗方式，可以使患者受益，甚至使复发患者受益。治疗结果通常是令人满意的，尤其是在散发病例中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurochirurgie 医学-临床神经学

CiteScore

2.70

自引率

6.20%

发文量

100

审稿时长

29 days

期刊介绍： Neurochirurgie publishes articles on treatment, teaching and research, neurosurgery training and the professional aspects of our discipline, and also the history and progress of neurosurgery. It focuses on pathologies of the head, spine and central and peripheral nervous systems and their vascularization. All aspects of the specialty are dealt with: trauma, tumor, degenerative disease, infection, vascular pathology, and radiosurgery, and pediatrics. Transversal studies are also welcome: neuroanatomy, neurophysiology, neurology, neuropediatrics, psychiatry, neuropsychology, physical medicine and neurologic rehabilitation, neuro-anesthesia, neurologic intensive care, neuroradiology, functional exploration, neuropathology, neuro-ophthalmology, otoneurology, maxillofacial surgery, neuro-endocrinology and spine surgery. Technical and methodological aspects are also taken onboard: diagnostic and therapeutic techniques, methods for assessing results, epidemiology, surgical, interventional and radiological techniques, simulations and pathophysiological hypotheses, and educational tools. The editorial board may refuse submissions that fail to meet the journal''s aims and scope; such studies will not be peer-reviewed, and the editor in chief will promptly inform the corresponding author, so as not to delay submission to a more suitable journal. With a view to attracting an international audience of both readers and writers, Neurochirurgie especially welcomes articles in English, and gives priority to original studies. Other kinds of article - reviews, case reports, technical notes and meta-analyses - are equally published. Every year, a special edition is dedicated to the topic selected by the French Society of Neurosurgery for its annual report.