Applications of Nanomedicine in Brain Tumor Therapy: Nanocarrierbased Drug Delivery Platforms, CChallenges, and Perspectives.

IF 2 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Ravinder Verma, Lakshita Rao, Harish Kumar, Nitin Bansal, Aakash Deep, Jatin Parashar, Manish Yadav, Vineet Mittal, Deepak Kaushik
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Abstract

Background: The most difficult kind of cancer to treat is brain cancer, which causes around 3% of all cancer-related deaths. The targeted delivery is improved with the use of technologies based on nanotechnology that are both safe and efficient. Because of this, there is now a lot of research being done on brain cancer treatments based on nanoformulations.

Objective: In this review, the author's primary aim is to elucidate the various nanomedicine for brain cancer therapy. The authors focus primarily on the advancement of nanotechnology in treating brain cancer (BC). This review article gives readers an up-to-date look at publications on sophisticated nanosystems in treating BC, including quantum dots (QDs), nanoparticles (NPs), polymeric micelles (PMs), dendrimers, and solid lipid nanoparticles (SLNs), among others. This article offers insight into the use of various nanotechnology-based systems for therapy as well as their potential in the future. This article also emphasizes the drawbacks of nanotechnology-based methods. Future perspectives for treating brain cancer using proteomics and biomimetic nanosystems are briefly discussed.

Conclusion: In this review, we review several aspects of brain cancer therapy, including various nanomedicines, their challenges and future perspectives. Overall, this article gives a thorough overview of both the present state of brain cancer treatment options and the disease itself.

纳米医学在脑肿瘤治疗中的应用:基于纳米载体的药物递送平台、挑战和展望。
背景:癌症最难治疗的是癌症,它导致了大约3%的癌症相关死亡。通过使用安全高效的基于纳米技术的技术,有针对性的交付得到了改善。正因为如此,现在有很多基于纳米制剂的癌症脑治疗研究正在进行中。目的:在这篇综述中,作者的主要目的是阐明用于脑癌症治疗的各种纳米药物。作者主要关注纳米技术在治疗癌症(BC)方面的进展。这篇综述文章让读者了解了治疗BC的复杂纳米系统的最新出版物,包括量子点(QDs)、纳米颗粒(NP)、聚合物胶束(PM)、树枝状聚合物和固体脂质纳米颗粒(SLN)等。本文深入了解了各种基于纳米技术的治疗系统的使用及其未来的潜力。本文还强调了基于纳米技术的方法的缺点。简要讨论了利用蛋白质组学和仿生纳米系统治疗癌症的未来前景。结论:在这篇综述中,我们回顾了脑癌症治疗的几个方面,包括各种纳米药物、它们的挑战和未来前景。总之,本文对癌症治疗方案的现状和疾病本身进行了全面的概述。
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来源期刊
Recent Patents on Nanotechnology
Recent Patents on Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
4.70
自引率
10.00%
发文量
50
审稿时长
3 months
期刊介绍: Recent Patents on Nanotechnology publishes full-length/mini reviews and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of nanotechnology. A selection of important and recent patents on nanotechnology is also included in the journal. The journal is essential reading for all researchers involved in nanotechnology.
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