Vitamin K - a scoping review for Nordic Nutrition Recommendations 2023.

IF 3.5 4区 医学 Q2 FOOD SCIENCE & TECHNOLOGY
Food & Nutrition Research Pub Date : 2023-10-23 eCollection Date: 2023-01-01 DOI:10.29219/fnr.v67.10260
Arja T Lyytinen, Allan Linneberg
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Abstract

Vitamin K occurs in dietary supply in two major forms: phylloquinone (vitamin K1) and menaquinones (collectively referred as vitamin K2). Phylloquinone is derived from plants. There are at least 10 forms of menaquinones varying in chain length and they are produced by bacteria except menaquinone-4. Menaquinone-4 is formed from phylloquinone or other menaquinone forms. Phylloquinone is considered to be the major contributor and menaquinones are thought to contribute less to vitamin K intake in Western diets. However, less is known about the content of menaquinones than phylloquinones in foods. Vitamin K is known to function as an enzymatic cofactor in the gamma-carboxylation of vitamin K dependent proteins (VKDPs). Hepatic VKDPs are involved in coagulation. Extrahepatic VKDPs have a role e.g. in bone health and vascular calcification. However, the amount of vitamin K needed for optimal functioning of the different VKDPs is not known.

Abstract Image

维生素K——2023年北欧营养建议的范围审查。
维生素K以两种主要形式存在于膳食中:叶醌(维生素K1)和甲萘醌(统称为维生素K2)。Phylloquinone来源于植物。至少有10种形式的甲萘醌链长不同,它们是由除甲萘醌-4外的细菌产生的。醌-4由叶醌或其他形式的醌形成。Phylloquinone被认为是主要的贡献者,而在西方饮食中,menaquinones被认为对维生素K摄入的贡献较小。然而,人们对食物中甲萘醌的含量知之甚少。已知维生素K在维生素K依赖性蛋白质(VKDPs)的γ羧化中起酶促辅因子的作用。肝VKDP参与凝血。肝外VKDP在骨健康和血管钙化中发挥作用。然而,不同VKDP的最佳功能所需的维生素K的量尚不清楚。
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来源期刊
Food & Nutrition Research
Food & Nutrition Research FOOD SCIENCE & TECHNOLOGY-NUTRITION & DIETETICS
CiteScore
5.20
自引率
9.10%
发文量
47
审稿时长
14 weeks
期刊介绍: Food & Nutrition Research is a peer-reviewed journal that presents the latest scientific research in various fields focusing on human nutrition. The journal publishes both quantitative and qualitative research papers. Through an Open Access publishing model, Food & Nutrition Research opens an important forum for researchers from academic and private arenas to exchange the latest results from research on human nutrition in a broad sense, both original papers and reviews, including: * Associations and effects of foods and nutrients on health * Dietary patterns and health * Molecular nutrition * Health claims on foods * Nutrition and cognitive functions * Nutritional effects of food composition and processing * Nutrition in developing countries * Animal and in vitro models with clear relevance for human nutrition * Nutrition and the Environment * Food and Nutrition Education * Nutrition and Economics Research papers on food chemistry (focus on chemical composition and analysis of foods) are generally not considered eligible, unless the results have a clear impact on human nutrition. The journal focuses on the different aspects of nutrition for people involved in nutrition research such as Dentists, Dieticians, Medical doctors, Nutritionists, Teachers, Journalists and Manufacturers in the food and pharmaceutical industries.
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