Muscle cramps in liver cirrhosis

Q4 Medicine

胃肠病学 Pub Date : 1989-09-01 DOI:10.6557/GJTA.198909_6(3).0003

Y. Chao, F. Lee, Y. Tsai, Hanyang Lin, Ting Chang, Sung-Sang Wang, Jaw‐Ching Wu, K. Lai, Shou-Dong Lee, K. Lo

引用次数: 8

Abstract

A high incidence (64%) of muscle cramps was found in 112 cirrhotic patients, as compared with 17% in 169 hepatitis B surface antigen (HBsAg) negative healthy persons, 8% in 13 asymptomatic HBsAg carriers, 8% in 12 patients with acute hepatitis, and 28% in 25 patients with chronic hepatitis. The cramps were characterized by severe pain with more than one episode per week which occurred mainly during sleep in the lower extremities and lasted for few minutes. Besides the use of diuretics and the presence of peripheral edema, no definite etiologic factors could be found. The underlying pathophysiology of muscle cramps in patients with chronic liver disease remains obscure. However, the strikingly high incidence of muscle cramps could be recognized as a symptom of cirrhosis.

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肝硬化引起肌肉痉挛

112例肝硬化患者肌肉痉挛发生率高(64%)，而169例乙型肝炎表面抗原(HBsAg)阴性的健康人肌肉痉挛发生率为17%，13例无症状HBsAg携带者为8%，12例急性肝炎患者为8%，25例慢性肝炎患者为28%。痉挛的特点是剧烈疼痛，每周发作一次以上，主要发生在下肢睡眠时，持续几分钟。除了使用利尿剂和周围水肿外，没有明确的病因。慢性肝病患者肌肉痉挛的潜在病理生理学仍不清楚。然而，高发生率的肌肉痉挛可能被认为是肝硬化的症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

胃肠病学 Medicine-Gastroenterology

CiteScore

0.10

自引率

0.00%

发文量

4567

期刊介绍： Gastroenterology is an academic journal sponsored by Shanghai Jiao Tong University School of Medicine. It mainly publishes original research papers, reviews and comments in this field. The journal was founded in 1996 and is included in well-known databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences) and Statistical Source Journal (China's Excellent Science and Technology Papers Journal). It is one of the national key academic journals under the jurisdiction of the Ministry of Education. Gastroenterology enjoys a high reputation and influence in the academic community. The articles published in this journal have a high academic level and practical value, providing readers with more actual cases and industry information, and have received widespread attention and citations from readers.