{"title":"Personalized medicine approach to osteoporosis management in women: integrating genetics, pharmacogenomics, and precision treatments","authors":"Seyi Samson Enitan, Esther Ngozi Adejumo, John Osaigbovoh Imaralu, Ayodele Ademola Adelakun, Oluwakemi Anike Ladipo, Comfort Bosede Enitan","doi":"10.53388/crc2023018","DOIUrl":null,"url":null,"abstract":"Osteoporosis has emerged as a significant health issue among postmenopausal women. Addressing this concern necessitates a multifaceted approach encompassing genetics, pharmacogenomics, bone turnover markers, lifestyle factors, concurrent medical conditions, biomarkers, and advanced imaging techniques. Nonetheless, challenges in terms of cost-effectiveness and ethical considerations do exist. Fortunately, the convergence of technological progress and research endeavors offers a promising trajectory. The integration of genetic testing and pharmacogenomics into clinical practice holds substantial potential. This integration empowers healthcare professionals to forecast treatment responses and pinpoint individuals with elevated susceptibility, thereby enabling the implementation of tailored and efficacious interventions that optimize outcomes – personalized medicine. Given the intricate nature of osteoporosis, personalized strategies stand to greatly benefit women grappling with this condition. Further research and collaborative efforts are imperative to propel advancements within this domain, paving the way for further breakthroughs.","PeriodicalId":72626,"journal":{"name":"Clinical research communications","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical research communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53388/crc2023018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Osteoporosis has emerged as a significant health issue among postmenopausal women. Addressing this concern necessitates a multifaceted approach encompassing genetics, pharmacogenomics, bone turnover markers, lifestyle factors, concurrent medical conditions, biomarkers, and advanced imaging techniques. Nonetheless, challenges in terms of cost-effectiveness and ethical considerations do exist. Fortunately, the convergence of technological progress and research endeavors offers a promising trajectory. The integration of genetic testing and pharmacogenomics into clinical practice holds substantial potential. This integration empowers healthcare professionals to forecast treatment responses and pinpoint individuals with elevated susceptibility, thereby enabling the implementation of tailored and efficacious interventions that optimize outcomes – personalized medicine. Given the intricate nature of osteoporosis, personalized strategies stand to greatly benefit women grappling with this condition. Further research and collaborative efforts are imperative to propel advancements within this domain, paving the way for further breakthroughs.