Efficacy of epidural steroid injection in management of lumbar disc lesion

Hussein El-Ghait, A. Akar, Abdelazim Hegazy, Mahmoud El-Maadawy
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引用次数: 3

Abstract

Background and aim Low back pain and radiculopathy are the main annoying complaints in patients with degenerative disc diseases. Epidural steroid injection (ESI) has a role to reduce pain and improve disability by decreasing inflammatory process at the nerve root caused by herniated disc. This study was done to evaluate the efficacy of lumbar ESI regarding the improvement of pain and functional outcome. Patients and methods This study was a prospective randomized study on 30 patients, aged between 30 and 65 years with low back pain and lumbar radiculopathy secondary to lumbar disc prolapse with no absolute indication for surgery. The patients were treated by lumbar epidural injection of steroids. Patients were divided randomly into two groups: group 1 included 15 patients subjected to lumbar interlaminar ESI, and group 2 included 15 patients subjected to lumbar transforaminal ESI. Patients were evaluated using visual analog scale (VAS) score for pain and the Oswestry Disability Index (ODI) for functional capacity. They were followed up after 4 weeks, and clinical and functional outcomes were assessed using the same tools for evaluation. Results The mean VAS for the 30 patients improved by 58.33% (P<0.001), and the mean ODI for the 30 patients improved by 35.4% after 4 weeks following injection (P<0.001). In group 1, the mean VAS improved by 52% and the mean ODI improved by 31.13% after 4 weeks following injection (P<0.001). In group 2, the mean VAS improved by 64.66% and the mean ODI improved by 39.66% after 4 weeks following injection (P<0.001). We found that the mean improvement of VAS and ODI was more in group 2 than in group 1(P<0.026). Conclusion We found by the end of the study that the ESI is a safe and effective procedure in alleviating radicular pain and improvement of functional outcome, but the transforaminal approach gives better results than the interlaminar approach.
硬膜外注射类固醇治疗腰椎间盘病变的疗效观察
背景与目的腰痛和神经根病是椎间盘退行性疾病患者的主要主诉。硬膜外类固醇注射(ESI)通过减少椎间盘突出引起的神经根炎症过程来减轻疼痛和改善残疾。本研究旨在评估腰椎ESI在改善疼痛和功能预后方面的疗效。患者和方法本研究是一项前瞻性随机研究,纳入30例年龄在30 - 65岁之间的腰痛和腰椎间盘突出症患者,无绝对手术指征。采用腰椎硬膜外注射类固醇治疗。将患者随机分为两组:1组15例腰椎椎间腔内固定,2组15例腰椎椎间孔腔内固定。采用视觉模拟量表(VAS)对疼痛进行评分,并用Oswestry残疾指数(ODI)对功能能力进行评估。4周后进行随访,使用相同的评估工具评估临床和功能结果。结果30例患者注射后4周VAS平均改善58.33% (P<0.001), ODI平均改善35.4% (P<0.001)。第1组注射后4周VAS平均改善52%,ODI平均改善31.13% (P<0.001)。2组注射后4周VAS平均改善64.66%,ODI平均改善39.66% (P<0.001)。2组VAS和ODI的平均改善程度明显高于1组(P<0.026)。结论在研究结束时,我们发现ESI在缓解神经根疼痛和改善功能预后方面是一种安全有效的手术,但经椎间孔入路比椎间孔入路效果更好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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11
审稿时长
34 weeks
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