Morphological characteristics and immunophenotype of clear cell renal cell carcinomas

Abstract

Results. Based on the morphological analysis and immunohistochemical assay, the tumors were divided into 4 groups as follows: renal cystic tumors with low nuclear grading (n=65; 25%); tumors of a kidney of a solid and/or tubulo-papillary structure with low nuclear grading (n=98; 37%); renal tumors with high nuclear grading (n=94; 36%); and polyphase renal cell carcinomas (n=7; 2.7%). Conclusion. The results obtained suggest that there is a direct link between the degree of nuclear grading and the histological pattern of the tumor among the morphological forms of clear cell renal cell carcinoma.