Hepatitis C Virus Pathophysiology and Diagnosis

Abstract

Hepatitis C virus (HCV) is spherical enveloped RNA virus and belongs to Flaviviridae family , Parenteral exposure to the HCV is the most efficient means of transmission . Often Hepatitis C is diagnosed accidentally so, HCV diagnostic tests should be performed in all patients presenting with increased aminotransferase levels. The number of patients actually HCV RNA positive is estimated to be around 80 to 90% of all HCV-antibody positive persons the Genotype 4 is responsible for >90% of cases ,approximately 3% of the world’s population (roughly 170-200 million people) infected with hepatitis C virus with considerable regional variations.