The modern management of Grave’s disease in children

Abstract

Hyperthyroidism is a pathological condition characterized by over production of thyroid hormones (thyroxine (T4) and triiodothyronine (T3)) by the thyroid gland. The most often cause of hyperthyroidism in children is a diffuse toxic goiter (GD) with typical laboratory changes in blood and severe clinical duration. Signs and symptoms of hyperthyroidism in children are similar with adults, but in children we can find accelerated growth rates, increased fatigue and decreased academic performance. The article presents up-to-date data on the management of pediatric patients with GD with references to the 2022 clinical guidelines of the European Thyroid Association for the management of Graves' disease in children. Key words: hyperthyroidism, childhood , diffuse toxic goiter, thyroid gland