Metabolic therapy in the rehabilitation of children with the consequences of perinatal hypoxia

Abstract

Perinatal hypoxia is a common cause of developmental delays, disorders of the nervous and cardiovascular systems, and immune disorders. Early comprehensive rehabilitation of children with hypoxic lesions to the central nervous system can alleviate pathological manifestations and normalize the process of development. This review discusses different aspects of metabolic therapy for the rehabilitation of such children and describes the results of some studies assessing the efficacy of Glycine and Biotredin in children with various disorders. The combination of these two drugs proved to be effective in premature infants of various gestational age through normalizing their neurological status and improving weight and growth parameters. The article also describes the principles of metabolic correction of speech disorders in the critical preschool period, as well the mechanisms underlying the effect of the drugs on the cellular metabolism of the nervous system. Key words: hypoxia, metabolic therapy, preterm birth, glycine, speech disorders