Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC

IF 6.1 1区医学 Q1 ONCOLOGY

Breast Cancer Research Pub Date : 2022-06-03 DOI:10.1186/s13058-022-01531-1

M. Harrasser, S. Gohil, H. Lau, M. della Peruta, Vincent Muczynski, Dominic Patel, Elena Miranda, Kristiana Grigoriadis, A. Grigoriadis, D. Granger, R. Evans, A. Nathwani

引用次数: 8

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诱导局部递送抗pd -1 scFv增强TNBC中ROR1 CAR-T细胞的抗肿瘤活性

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来源期刊

Breast Cancer Research 医学-肿瘤学

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期刊介绍： Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer. In addition to basic research, the journal publishes preclinical, translational and clinical studies with a biological basis, including Phase I and Phase II trials.