{"title":"Colicinogeny and related phenomena.","authors":"K. G. Hardy","doi":"10.1128/MMBR.39.4.464-515.1975","DOIUrl":null,"url":null,"abstract":"INTRODUCTION .............................................................. TWO MAJOR GROUPS OF COLICIN FACTORS .............................. Relationships at the Level of Plasmid DNA.................................... Recombination Between Col Factors and Other Plasmids ...................... SURVIVAL OF COL FACTORS IN BACTERIAL CELLS: ADAPTATION TO THE HOST CELL ENVIRONMENT ............................................ Host Range................................................................. Experimental Approaches to the Problem ..................................... Regulation of the Number of Col Factors per Cell ............................. Functions Contributed by Hosts and by Col Factors ........................... Intermediates ................................................................ Incompatibility .............................................................. RELATIONSHIPS BETWEEN THE FERTILITY SYSTEMS OF COL FACTORS Sex Pili ..................................................................... Fertility Inhibition .......................................................... Exclusion ................................................................... Transfer of Chromosomal Genes .............................................. Transfer of Group I Col Factors .............................................. COLICINS .................................................................... Relationships Between Colicins.............................................. Colicin Synthesis in Relation to Lysogeny................................... EFFECTS OF COLICINS ON SENSITIVE BACTERIA ....................... Analogous Systems .......................................................... Initial Contact with the Cell: Receptors ....................................... Effects of Colicins on the Cytoplasmic Membrane ............................. Comparable Effects of Other Proteins......................................... Action of Colicins E3-CA38 and E2-P9 ........................................ Immunity to the Effects of Colicins, Bacteriophages, Bacteriophage Ghosts, and Sex Pili ................................................................... ECOLOGY OF COL FACTORS AND COLICINS.............................. Methods of Study ............................................................ Investigations Using Gnotobiotic Animals ..................................... Succession of Strains in the Intestine ......................................... Colicins and Disease ........................................................ Significance of Colicins Outside the Intestine ................................. ECOLOGY OF OTHER BACTERIOCINS ................................... Streptococcus ................................................................ Staphylococcus. Pseudomonas ................................................................ Pasteurella .................................................................. Neisseria .................................................................... CONCLUDING REMARKS .................................................... LITERATURE CITED .........................................................","PeriodicalId":55406,"journal":{"name":"Bacteriological Reviews","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1975-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"226","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bacteriological Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/MMBR.39.4.464-515.1975","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 226
Abstract
INTRODUCTION .............................................................. TWO MAJOR GROUPS OF COLICIN FACTORS .............................. Relationships at the Level of Plasmid DNA.................................... Recombination Between Col Factors and Other Plasmids ...................... SURVIVAL OF COL FACTORS IN BACTERIAL CELLS: ADAPTATION TO THE HOST CELL ENVIRONMENT ............................................ Host Range................................................................. Experimental Approaches to the Problem ..................................... Regulation of the Number of Col Factors per Cell ............................. Functions Contributed by Hosts and by Col Factors ........................... Intermediates ................................................................ Incompatibility .............................................................. RELATIONSHIPS BETWEEN THE FERTILITY SYSTEMS OF COL FACTORS Sex Pili ..................................................................... Fertility Inhibition .......................................................... Exclusion ................................................................... Transfer of Chromosomal Genes .............................................. Transfer of Group I Col Factors .............................................. COLICINS .................................................................... Relationships Between Colicins.............................................. Colicin Synthesis in Relation to Lysogeny................................... EFFECTS OF COLICINS ON SENSITIVE BACTERIA ....................... Analogous Systems .......................................................... Initial Contact with the Cell: Receptors ....................................... Effects of Colicins on the Cytoplasmic Membrane ............................. Comparable Effects of Other Proteins......................................... Action of Colicins E3-CA38 and E2-P9 ........................................ Immunity to the Effects of Colicins, Bacteriophages, Bacteriophage Ghosts, and Sex Pili ................................................................... ECOLOGY OF COL FACTORS AND COLICINS.............................. Methods of Study ............................................................ Investigations Using Gnotobiotic Animals ..................................... Succession of Strains in the Intestine ......................................... Colicins and Disease ........................................................ Significance of Colicins Outside the Intestine ................................. ECOLOGY OF OTHER BACTERIOCINS ................................... Streptococcus ................................................................ Staphylococcus. Pseudomonas ................................................................ Pasteurella .................................................................. Neisseria .................................................................... CONCLUDING REMARKS .................................................... LITERATURE CITED .........................................................