Issues related to the protection of human research participants.

Abstract

Making ethical decisions related to the protection of human research participants is often complex and fraught with uncertainty and conflict. Awareness of the basic principles outlined in the Belmont Report as well as in federal regulations and guidelines can provide a useful framework for such decisions, although the ultimate responsibility for ensuring ethical research practices rests with the individual investigator. Ongoing dialogue and discussion about these ethical issues will provide a basis for strengthening nursing research and practice while ensuring the maximum protection for research participants who make possible the advancement of nursing science.