Modelling of the adsorption of Cephalosporin C on modified resins in a stirred tank

Abstract

It has been shown that over the range of concentration used, the adsorption of Cephalosporin C can be characterized by a single linear adsorption constant. Additionally, the kinetics has been modelled successfully using both the linear adsorption isotherm and a single effective internal diffusion coefficient. The modelling work showed that the observed insensitivity of the goodness of fit to the effective Sherwood number was due to the fact that the method of agitation employed in the experiments was effective. The results hold in spite of the twofold variation in adsorption concentration in the liquid phase and the threefold variation in the square of the particle radius.