Blebs and former blebs: From surface protrusions to extracellular vesicles in cancer signalling, anoikis resistance and beyond

Dolores Di Vizio, Melanie Schoppet, Ashani Weeraratna, Kenneth W. Witwer
{"title":"Blebs and former blebs: From surface protrusions to extracellular vesicles in cancer signalling, anoikis resistance and beyond","authors":"Dolores Di Vizio,&nbsp;Melanie Schoppet,&nbsp;Ashani Weeraratna,&nbsp;Kenneth W. Witwer","doi":"10.1002/jex2.112","DOIUrl":null,"url":null,"abstract":"<p>Associations between plasma membrane blebbing and metastatic progression have been widely reported. There are also reports of increased extracellular vesicle (EV) release from cancer cells. Yet the ties between these closely related phenomena are incompletely understood. In this commentary, we remark on a recent finding on cellular membrane blebs in melanoma signalling. We discuss possible implications for cancer biology and draw parallels to knowns and unknowns in the relationships of EVs and cancer progression.</p>","PeriodicalId":73747,"journal":{"name":"Journal of extracellular biology","volume":"2 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jex2.112","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of extracellular biology","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jex2.112","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Associations between plasma membrane blebbing and metastatic progression have been widely reported. There are also reports of increased extracellular vesicle (EV) release from cancer cells. Yet the ties between these closely related phenomena are incompletely understood. In this commentary, we remark on a recent finding on cellular membrane blebs in melanoma signalling. We discuss possible implications for cancer biology and draw parallels to knowns and unknowns in the relationships of EVs and cancer progression.

Abstract Image

斑点和以前的斑点:从表面突起到癌症信号传导中的细胞外小泡,失活细胞耐药性及其他
质膜起泡与转移进展之间的关系已被广泛报道。也有报道称癌症细胞的细胞外囊泡(EV)释放增加。然而,人们对这些密切相关的现象之间的联系还不完全了解。在这篇评论中,我们评论了最近关于黑色素瘤信号传导中细胞膜泡的发现。我们讨论了对癌症生物学的可能影响,并将EVs与癌症进展之间的关系与已知和未知进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信