Prevalencia de dislipemia aterogénica, factores relacionados y grado de control lipídico en la población general de Galicia. Estudio GALIPEMIAS

IF 1.9 Q3 PERIPHERAL VASCULAR DISEASE

Clinica e Investigacion en Arteriosclerosis Pub Date : 2023-07-01 DOI:10.1016/j.arteri.2022.11.002

Carlos Názara , Rosa M. Argüeso , Juan Pedro-Botet , Xavier Pintó , Jesús Millán , Marta Pena Seijo , Pablo A. Fernández , M. Eugenia Ameneiros , Alberto del Alamo , Avelino Rodríguez , José Antonio Díaz-Peromingo , María Rosa Vázquez Freire , Javier Muñiz , Teresa R. Pérez-Castro , José Luis Díaz-Díaz , Antonio Pose Reino

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引用次数: 0

Abstract

Objectives

GALIPEMIAS is a study designed to establish the prevalence of familial dyslipidemia in the general population of Galicia. The objective of the present study was to assess the prevalence of atherogenic dyslipidemia (AD), its relationship with other cardiovascular risk (CVR) factors, and the degree of lipid control.

Methods

Cross-sectional study carried out in the general population over 18 years of age residing in Galicia and with a health card from the Galician Health Service (N = 1,000). Selection of the sample by means of random sampling by conglomerates. The AD prevalence adjusted for age and sex and the related variables were analyzed.

Results

The prevalence of AD adjusted for age and sex was 6.6% (95% CI: 5.0-8.3%). Arterial hypertension, altered basal glycemia, type 2 diabetes mellitus and cardiovascular disease were more frequent in subjects with AD than in the rest of the population. 47.5% of the subjects with AD had a high or very high CVR. Lipid-lowering drugs were received by 38.9% (30.5% statins) of the participants with AD (46.1% of those with high and 71.4% of those with very high CVR). 25.4% of the subjects with AD had target LDL-c levels, all of them with low or moderate CVR.

Conclusions

The prevalence of AD in the general adult population of Galicia is not negligible, and it was related to several CVR factors and cardiovascular disease. Despite this, this lipid alteration was underdiagnosed and undertreated.

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加利西亚普通人群动脉粥样硬化性血脂异常的患病率、相关因素和脂质控制程度。加利佩米亚斯研究

目的研究家族性血脂异常在加利西亚普通人群中的患病率。本研究的目的是评估动脉粥样硬化性血脂异常（AD）的患病率、其与其他心血管风险（CVR）因素的关系以及脂质控制程度。方法对居住在加利西亚并持有加利西亚卫生服务局健康卡（N=1000）的18岁以上普通人群进行横断面研究。通过企业集团随机抽样的方式选择样品。分析了经年龄和性别调整后的AD患病率以及相关变量。结果经年龄和性别校正后的AD患病率为6.6%（95%CI:5.0-8.3%），AD患者动脉高压、基础血糖改变、2型糖尿病和心血管疾病的发生率高于其他人群。47.5%的AD受试者具有高或非常高的CVR。38.9%（30.5%的他汀类药物）的AD患者（46.1%的高CVR患者和71.4%的极高CVR患者）服用了降脂药物。25.4%的AD受试者具有目标LDL-c水平，均具有低或中度CVR。结论在加利西亚的普通成年人群中，AD的患病率不容忽视，它与多种CVR因素和心血管疾病有关。尽管如此，这种脂质改变的诊断和治疗都不足。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinica e Investigacion en Arteriosclerosis PERIPHERAL VASCULAR DISEASE-

CiteScore

3.20

自引率

6.20%

发文量

审稿时长

40 days

期刊介绍： La publicación idónea para acceder tanto a los últimos originales de investigación como a formación médica continuada sobre la arteriosclerosis y su etiología, epidemiología, fisiopatología, diagnóstico y tratamiento. Además, es la publicación oficial de la Sociedad Española de Arteriosclerosis.