Cutaneous Cytomegalovirus Infection Presenting As Recalcitrant Bullous Pemphigoid Lesion.

Gayun Baek, Taehan Koo, Min-Soo Kim, Mihn-Sook Jue
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引用次数: 1

Abstract

Cytomegalovirus (CMV) infection is common among immunocompromised hosts; however, its cutaneous manifestation is considered rare in comparison to internal organ involvement. Clinical manifestations of cutaneous CMV infection generally include perioral or perianal ulcerations. On the other hand, autoimmune bullous dermatosis can have bullae and ulcerations similar to those caused by cutaneous CMV infection. Autoimmune bullous dermatosis requires treatment with immunosuppressive agents for relatively long periods, which may cause reduction of immunocompetence. Because of this iatrogenic immunosuppression, patients with autoimmune bullous dermatosis subsequently acquire increased risk for opportunistic infections. However, cases of bullous pemphigoid (BP) complicated by cutaneous CMV infection are rarely reported. Herein, we report the case of an 88-year-old male who had BP and subsequently recalcitrant perianal skin lesions, which were eventually diagnosed as cutaneous CMV infections.

Abstract Image

Abstract Image

皮肤巨细胞病毒感染表现为顽固性大疱性类天疱疮。
巨细胞病毒(CMV)感染在免疫功能受损的宿主中很常见;然而,与内脏受累相比,其皮肤表现被认为是罕见的。皮肤巨细胞病毒感染的临床表现通常包括口周或肛周溃疡。另一方面,自身免疫性大疱性皮肤病可出现类似于皮肤巨细胞病毒感染引起的大疱和溃疡。自身免疫性大疱性皮肤病需要用免疫抑制剂治疗相对较长的时间,这可能会导致免疫活性降低。由于这种医源性免疫抑制,自身免疫性大疱性皮肤病患者随后获得机会性感染的风险增加。然而,大疱性类天疱疮(BP)并发皮肤巨细胞病毒感染的病例很少报道。在此,我们报告了一例88岁的男性,他患有BP,随后出现顽固性肛周皮肤病变,最终被诊断为皮肤CMV感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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