Indocyanine Green Fluorescence in Colorectal Cancer

IF 2.7 Q3 ONCOLOGY

Colorectal Cancer Pub Date : 2020-11-03 DOI:10.5772/intechopen.94375

E. Vargas, C. Ginestà

引用次数: 0

Abstract

Fluorescence vision using indocyanine green is a surgical tool with increasing applications in colorectal cancer surgery. This tool has received acceptance in several disciplines as a potential method to improve visualization of the surgical field, improve lymph node resection and decrease the incidence of anastomotic leaks (ALs). In colorectal surgery specifically, some studies have shown that intraoperative fluorescence imaging is a safe and feasible method to evaluate anastomotic perfusion, and its use could affect the incidence of anastomotic leaks. Currently, controlled trials are carried out to validate these conclusions, as well as new indications for indocyanine green such as detection and guidance in the management of hepatic colorectal metastases, visualization of ureters and even as tumor marking and improvement the lymph node harvest of early tumors. These advances could offer great value to surgeons and patients, by improving the accuracy and results of cancer resections.

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癌症大肠癌组织中的吲哚青绿荧光

使用吲哚青绿的荧光视觉是一种外科工具，在结直肠癌癌症手术中的应用越来越多。该工具已被多个学科认可为一种潜在的方法，可以改善手术视野的可视化，改善淋巴结切除，降低吻合口瘘（ALs）的发生率。特别是在结直肠手术中，一些研究表明，术中荧光成像是一种安全可行的评估吻合口灌注的方法，其使用可能会影响吻合口瘘的发生率。目前，正在进行对照试验来验证这些结论，以及吲哚青绿的新适应症，如肝结直肠癌转移的检测和指导、输尿管的可视化，甚至作为肿瘤标记和改善早期肿瘤的淋巴结收获。这些进步可以通过提高癌症切除的准确性和结果，为外科医生和患者提供巨大的价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colorectal Cancer ONCOLOGY-

自引率

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发文量

期刊介绍： Colorectal cancer is a major cause of morbidity and mortality, particularly in the developed world. Risk factors for colorectal cancer are on the rise in many countries; populations are aging, and obesity and diabetes are increasing. National screening programs are helping to detect cancer while it is still curable; however, colorectal cancer remains the third leading cause of cancer deaths in the USA and options are still limited for those with more advanced disease. Consequently, colorectal cancer is a major research priority for government, pharmaceutical companies and non-profit organizations. Research into diagnosis and optimum treatment of the disease is progressing rapidly, with new advances reported every day. Colorectal Cancer presents reviews, analysis and commentary. on all aspects of colorectal cancer.