Frailty in Survival Analysis of Widowhood Mortality

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2018-10-02 DOI:10.1155/2018/2378798

E. Ytterstad

引用次数: 2

Abstract

Heterogeneity between individuals has attracted attention in the literature of survival analysis for several decades. Widowed individuals also differ; some are more frail than others and thereby have a higher risk of dying. The traditional hazard rate in a survival model is a measure of population risk and does not provide direct information on the unobservable individual risk. A frailty model is developed and applied on a large Norwegian data set of 452 788 widowed individuals. The model seemed to fit the data well, for both widowers and widows in all age groups. The random frailty term in the model is significant, meaning that widowed persons may have individual hazard rates.

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寡妇死亡率的生存脆弱性分析

几十年来，个体之间的异质性在生存分析文献中引起了人们的关注。丧偶的人也各不相同；有些人比其他人更虚弱，因此死亡的风险更高。生存模型中的传统风险率是对人群风险的衡量，并不能提供关于不可观察的个体风险的直接信息。开发了一个虚弱模型，并将其应用于挪威452788名丧偶者的大型数据集。该模型似乎很适合所有年龄组的鳏夫和寡妇的数据。模型中的随机脆弱性术语是显著的，这意味着丧偶者可能具有个体风险率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.