A study of changes in Mean Ocular Perfusion Pressure and Intra-Ocular Pressure among patients undergoing hemodialysis

Perspectives In Medical Research Pub Date : 2022-08-30 DOI:10.47799/pimr.1002.05

D. Seethalakshmi, Savitha Kanakapur, Supriya Dk

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Abstract

Abstract Background:During hemodialysis there is decrease in both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and hence Mean Arterial Pressure (MAP) due to decrease in body fluid volume. Due to reduction in MAP there is decrease in Mean Ocular Perfusion Pressure (MOPP) and also there is increase in IOP during dialysis. Objective:To study changes in MOPP and IOP among patients undergoing hemodialysis Methods:An observational study was carried out among 100 patients undergoing hemodialysis Under aseptic condition, Proparacaine eye drops were instilled in both eyes, IOP was measured by Schiotz Indentation Tonometer 30 min before, during hemodialysis and 30 min after hemodialysis in supine position. Tonometer was sterilized by Isopropyl alcohol and was washed with normal saline before using on next patient. Systolic and diastolic blood pressure were measured by using sphygmomanometer 30 min before, during and 30 min after hemodialysis. Results:The variations in the SBP, DBP and MAP before, during and after hemodialysis were not statistically significant (p>0.05). There was significant differences for IOP between before, during and after hemodialysis and same for MOPP except before and 30 min after hemodialysis (p < 0.0001). Conclusion:Significant fluctuations were seen from the present study in the intra-ocular pressure and mean ocular perfusion pressure during, before and after hemodialysis.

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血液透析患者平均眼灌注压和眼内压变化的研究

摘要背景：在血液透析过程中，由于体液量的减少，收缩压（SBP）和舒张压（DBP）都会降低，因此平均动脉压（MAP）也会降低。由于MAP的降低，平均眼部灌注压（MOPP）降低，透析期间IOP也增加。目的：研究血液透析患者的MOPP和IOP的变化。方法：对100例血液透析患者进行观察研究。在无菌条件下，将丙卡因滴眼液滴入双眼，仰卧位用Schiotz压痕眼压计测量血液透析前30min、透析中30min和透析后30min的IOP。Tonometer用异丙醇消毒，并在下一位患者使用前用生理盐水清洗。在血液透析前、透析中和透析后30min使用血压计测量收缩压和舒张压。结果：血液透析前后SBP、DBP、MAP变化无统计学意义（p>0.05），除血透前和血透后30min外，MOPP的眼压和平均眼灌注压均存在显著波动（p＜0.0001）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Perspectives In Medical Research

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6 weeks