Insect Antimicrobial Peptides –Therapeutic and Agriculture Perspective

Q3 Biochemistry, Genetics and Molecular Biology

Journal of Applied Biotechnology Reports Pub Date : 2021-09-27 DOI:10.30491/JABR.2020.236075.1242

Habeeb Shaik Mohideen, Henry Louis

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引用次数: 2

Abstract

Antimicrobial resistance (AMR) has become a menace for humanity. Several antibiotics have become ineffective, and there is a need for a novel route or approach to finding solutions. Antimicrobial peptides (AMPs) have already generated a lot of noise for over four decades. However, insect-based AMPs offer not only novel sources but also provide effective measures, as the insects are known to be exposed to extreme environments. Plenty of insect-based AMPs have been identified from different orders of insect taxonomy. This review concentrates on the world of insect-based AMPs, their known targets and their applications in agriculture and medical fields. Transgenic induction of AMPs in different hosts has been successfully studied in plant systems. By identifying new AMPs, it will also help in the field of agriculture to increase the production rate of the crops by eliminating the disease-causing pathogens, microbes, and pests. In the present review, we have discussed recent knowledge, and several essential medical and agricultural importance of AMPs identified from insects.

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昆虫抗菌肽-治疗和农业前景

抗菌素耐药性(AMR)已成为人类的一大威胁。几种抗生素已经失效，需要一种新的途径或方法来寻找解决方案。四十多年来，抗菌肽(AMPs)已经产生了很多噪音。然而，基于昆虫的amp不仅提供了新的来源，而且还提供了有效的措施，因为已知昆虫暴露于极端环境中。从昆虫分类学的不同目中已经发现了大量的昆虫基amp。本文综述了昆虫类抗菌肽的研究现状、已知靶点及其在农业和医疗领域的应用。在植物系统中已经成功地研究了AMPs在不同寄主中的转基因诱导。通过鉴定新的抗菌肽，它还将有助于农业领域通过消除致病病原体、微生物和害虫来提高作物的产量。在本综述中，我们讨论了最近的知识，以及从昆虫中鉴定的几种基本的抗菌肽在医学和农业上的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Applied Biotechnology Reports Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： The Journal of Applied Biotechnology Reports (JABR) publishes papers describing experimental work relating to all fundamental issues of biotechnology including: Cell Biology, Genetics, Microbiology, Immunology, Molecular Biology, Biochemistry, Embryology, Immunogenetics, Cell and Tissue Culture, Molecular Ecology, Genetic Engineering and Biological Engineering, Bioremediation and Biodegradation, Bioinformatics, Biotechnology Regulations, Pharmacogenomics, Gene Therapy, Plant, Animal, Microbial and Environmental Biotechnology, Nanobiotechnology, Medical Biotechnology, Biosafety, Biosecurity, Bioenergy, Biomass, Biomaterials and Biobased Chemicals and Enzymes. Journal of Applied Biotechnology Reports promotes a special emphasis on: -Improvement methods in biotechnology -Optimization process for high production in fermentor systems -Protein and enzyme engineering -Antibody engineering and monoclonal antibody -Molecular farming -Bioremediation -Immobilizing methods -biocatalysis