Brain Neuroplasticity after Treatment with Antiseizure: A Review.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2023-11-30 Epub Date: 2023-06-07 DOI:10.9758/cpn.23.1058

Débora Lopes Silva de Souza, Hosana Mirelle Goes E Silva Costa, Francisca Idalina Neta, Paulo Leonardo Araujo de Gois Morais, Luís Marcos de Medeiros Guerra, Fausto Pierdoná Guzen, Lucídio Clebeson de Oliveira, JoséRodolfo Lopes de Paiva Cavalcanti, Cynthia Cavalcanti de Albuquerque, Claudio Lopes de Vasconcelos

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Abstract

Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.

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抗癫痫治疗后的脑神经可塑性:综述

癫痫是一种以周期性发作为特征的疾病。癫痫发作可以通过抗癫痫药物来控制，如果给予适当的治疗，可以改善癫痫患者的生活。因此，本研究旨在回顾在大脑不同区域使用抗癫痫药物治疗后大脑神经可塑性的科学文献。根据研究结果，几种抗癫痫药物，如拉莫三嗪、地西泮、左乙拉西坦和丙戊酸，除了控制癫痫发作外，还可以对不同大脑区域的神经可塑性起作用。这一主题的研究变得很重要，因为它将有助于了解这些药物的神经可塑性机制，并有助于提高这些药物在控制疾病方面的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464