Mono- and sesquiterpenes as a starting platform for the development of antiviral drugs

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Reviews Pub Date : 2021-04-01 DOI:10.1070/RCR4969

O. Yarovaya, N. Salakhutdinov

引用次数: 13

Abstract

The revies focuses on low-molecular-weight plant metabolites (mono- and sesquiterpenes) exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts and their components are provided. Structures of biologically active natural mono- and sesquiterpenoids as well as their derivatives showing a pronounced antiviral activity are presented. A special attention is given to the description of targets for antiviral therapy. The mechanisms of action of antiviral agents are considered. The bibliography includes 163 references.

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单萜类和倍半萜类作为开发抗病毒药物的起始平台

本文综述了具有抗病毒活性的低分子植物代谢物(单萜类和倍半萜类)。提供了精油和植物提取物及其成分抗病毒作用的数据。介绍了具有生物活性的天然单萜类和倍半萜类及其衍生物的结构，它们具有明显的抗病毒活性。特别注意抗病毒治疗的靶标描述。讨论了抗病毒药物的作用机制。参考书目包括163篇参考文献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Chemical Reviews 化学-化学综合

CiteScore

13.00

自引率

5.20%

发文量

审稿时长

6-12 weeks

期刊介绍： Russian Chemical Reviews serves as a complete translation of the esteemed monthly review journal Uspekhi Khimii, which has been a prominent figure in Russian scientific journals since its establishment in 1932. It offers comprehensive access to the advancements made by chemists from Russia and other former Soviet Union countries. Established in 1932, Russian Chemical Reviews is committed to publishing timely and significant review articles encompassing various facets of modern chemistry, including chemical physics, physical chemistry, computational and theoretical chemistry, catalysis, coordination chemistry, analytical chemistry, organic, organometallic, and organoelement chemistry, chemistry of macromolecules, applied chemistry, biochemistry, bio-organic chemistry, biomolecular chemistry, medicinal chemistry, materials chemistry, nanochemistry, nanostructures, and environmental chemistry.