Pattern of Rectal Cancer Recurrence Following Potentially Curative Surgical Treatment

Q4 Medicine
Gustavo Sevá-Pereira, Vitória de Souza Oliveira, G. Ribeiro, P. Tarabay, Marcello I Rabello, Joaquim José de Oliveira-Filho
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引用次数: 0

Abstract

Abstract Survival in rectal cancer has been related mainly to clinical and pathological staging. Recurrence is the most challenging issue when surgical treatment of rectal cancer is concerned. This study aims to establish a recurrence pattern for rectal adenocarcinoma submitted to surgical treatment between June 2003 and July 2021. After applying the exclusion criteria to 305 patients, 166 patients were analyzed. Global recurrence was found in 18.7% of them, while 7.8% have had local recurrence. Recurrences were diagnosed from 5 to 92 months after the surgical procedure, with a median of 32.5 months. Follow-up varied from 6 to 115 months. Recurrence, in literature, is usually between 3 and 35% in 5 years and shows a 5-year survival rate of only 5%. In around 50% of cases, recurrence is local, confined to the pelvis. This study was consonant with the literature in most aspects evaluated, although a high rate of local recurrence remains a challenge in seeking better surgical outcomes.
潜在治疗性外科治疗后直肠癌症复发的模式
直肠癌的生存主要与临床和病理分期有关。在直肠癌手术治疗中,复发是最具挑战性的问题。本研究旨在建立2003年6月至2021年7月期间接受手术治疗的直肠腺癌的复发模式。对305例患者应用排除标准,对166例患者进行分析。18.7%的患者全身复发,7.8%的患者局部复发。术后5 - 92个月诊断复发,中位数为32.5个月。随访时间从6至115个月不等。在文献中,5年内的复发率通常在3 - 35%之间,5年生存率仅为5%。在大约50%的病例中,复发是局部的,局限于骨盆。尽管高局部复发率仍然是寻求更好手术结果的挑战,但该研究在大多数方面与文献评估一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Coloproctology
Journal of Coloproctology Medicine-Gastroenterology
CiteScore
0.60
自引率
0.00%
发文量
41
审稿时长
47 weeks
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