Extreme Sleep Spindles in Children with Autism Spectrum Disorder and Related Disorders—A Case Series

Abstract

Abstract Extreme sleep spindles have fast activity and high amplitude, unlike normal sleep spindles. We report a case series of six children with autism and related disorders who had extreme spindles as noted on the sleep electroencephalogram recording at our center. We examine the types of extreme spindles, describe the clinical profiles of the 6 children, and discuss similar clinical and neurophysiological conditions.