Oral Colonization by Nosocomial Pathogens During Hospitalization in Intensive Care Unit and Prevention Strategies.

Q3 Medicine
H. Kazemian, Samaneh Bourbour, M. Beheshti, A. Bahador
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引用次数: 10

Abstract

BACKGROUND Critically ill patients are very susceptible to a variety of disorders and infections during hospitalization in Intensive Care Units [ICU]. Among these problems, nosocomial infections are major causes of morbidity and mortality. METHODS Nosocomial pneumonias, specifically ventilator associated pneumonias have become a major health care issue. The implication of oral care in hospital presents challenges that can prevent or reduce the risk of nosocomial pneumonias in ICU. In this review article, we reviewed the most important nosocomial pathogens which colonize the oral cavity and causes severe infections during hospitalization in ICU. CONCLUSION Finally, we discuss that the prevention strategies against oral colonization of nosocomial pathogens include classical methods and novel methods such as Photodynamic therapy, NO based therapy, anti-virulence therapy and other new under investigation antimicrobial strategies.
重症监护病房住院期间院内病原菌的口腔定植及预防策略。
背景危重患者在重症监护病房(ICU)住院期间极易发生各种疾病和感染。在这些问题中,医院感染是发病率和死亡率的主要原因。方法肺社会性肺炎,特别是呼吸机相关性肺炎已成为一个主要的卫生保健问题。医院口腔护理的含义提出了可以预防或降低ICU院内肺炎风险的挑战。在这篇综述文章中,我们回顾了在ICU住院期间最重要的定殖口腔并引起严重感染的院内病原菌。结论最后,我们讨论了预防院内病原菌口腔定植的方法,包括传统方法和新型方法,如光动力治疗、NO基础治疗、抗毒治疗和其他正在研究的新型抗菌策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Recent patents on anti-infective drug discovery
Recent patents on anti-infective drug discovery Medicine-Pharmacology (medical)
CiteScore
2.40
自引率
0.00%
发文量
1
期刊介绍: Recent Patents on Anti-Infective Drug Discovery publishes review articles on recent patents in the field of anti-infective drug discovery e.g. novel bioactive compounds, analogs & targets. A selection of important and recent patents on anti-infective drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-infective drug design and discovery.
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