Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

Q4 Medicine

Forum of Clinical Oncology Pub Date : 2021-12-01 DOI:10.2478/fco-2021-0010

E. Karamitrousis, I. Balgkouranidou, N. Xenidis, K. Amarantidis, E. Biziota, T. Koukaki, S. Kakolyris

引用次数: 1

Abstract

Abstract Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.

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转移性胃癌患者循环肿瘤DNA浓度及其预后意义

胃癌是世界范围内最常见的肿瘤之一。胃癌患者血液中游离DNA (cfDNA)含量高于健康对照组(69.1 ng/μL vs. 34.8 ng/μL)。cfDNA≤50 ng/μL的患者总生存期(OS)和无进展生存期(PFS)均高于cfDNA≤50 ng/μL的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊