COVID-19 in Nepal: Diagnostic and Management Dilemma

P. Subedi, Rajiv Khadge, S. Timilsina, K. Poudel
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引用次数: 0

Abstract

An outbreak of coronavirus disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) has created a global health crisis.1 Globally, there have been more than 53 million confirmed cases causing more than 1.2 million deaths.2 Although the World Health Organization (WHO) reports an overall decrease in weekly cases in Southeast Asia, COVID-19 cases are rising sharply in Nepal.3 As of November 12, 2020, Nepal has documented the pandemic in all seven provinces and 77 districts, confirming 204 242 cases and 1189 deaths (Figure 1).4 Out of the total number of confirmed cases, 164 592 cases have recovered while 38461 active cases are in self-quarantine via home isolation. Among critically ill patients with COVID-19, 379 are in the intensive care unit (ICU) from which 78 cases are on ventilation support.2,4 Due to the limited critical care delivery infrastructure, the COVID-19 pandemic has caused an unparalleled health crisis in Nepal. There is a lack of adequate PPE (personal protective equipment), standardized quarantine and isolation system, and insufficient testing kits for SARS-CoV-2 detection in the laboratory creating health havoc nationwide. Since the government has lifted the nearly four-month lockdown, the numbers of COVID-19 infected cases and death tolls are skyrocketing in Nepal. To identify people infected with SARS-CoV-2 and prevent the further spread of the disease, diagnostic testing remains crucial.5 Currently, a total of 67 COVID-19 designated diagnostic laboratories in Nepal, of which approximately a third are from the private sector. With the rise of newly infected cases throughout the nation, most of the diagnostic laboratories are facing shortages of reagent supply, instrument access, and increased staffing needs. Consequently, swab samples collected for testing are being piled up in the laboratories resulting in a serious delay in sample processing and their results.6,7 This situation has further resulted in frustration, boredom, and infection fears among people living in various quarantine and isolation centers across the country. The ongoing, unprecedented outbreak of COVID-19 is straining the laboratory services and other areas of healthcare interventions in Nepal. Even though the WHO considers the necessity for countries to prioritize diagnostic testing to contain the coronavirus spread,8 Nepalese government is not doing adequate testing while lacking timely decisions that are based on scientific evidence.9 Adequate testing means fewer people in unnecessary quarantine, lower load on hospitals, and faster contact tracing accordingly preventing onward transmission and spread of the disease. Therefore, the government of Nepal should emphasize more on molecular diagnostic technologies for COVID-19 and make the diagnostic facilities affordable and accessible in all districts of Nepal. Additionally, to limit the socio-economic and mental health burden of the ongoing pandemic,9 both the states and the federal government in http://ijtmgh.com Int J Travel Med Glob Health. 2020 Nov;8(4):174-175 doi 10.34172/ijtmgh.2020.30 TMGH IInternational Journal of Travel Medicine and Global Health J
尼泊尔的COVID-19:诊断和管理困境
由新型冠状病毒(SARS-CoV-2)引起的2019冠状病毒病(新冠肺炎)的爆发引发了全球健康危机。1全球确诊病例超过5300万例,导致120多万人死亡。2尽管世界卫生组织(世界卫生组织)报告东南亚每周病例总体下降,新冠肺炎病例在尼泊尔急剧上升。3截至2020年11月12日,尼泊尔在所有七个省和77个区记录了疫情,确认了204242例病例和1189例死亡(图1)。4在确诊病例总数中,164592例病例已康复,38461例活跃病例正在通过居家隔离进行自我隔离。在新冠肺炎危重症患者中,379人在重症监护室(ICU),78人在那里接受通气支持。2,4由于重症监护基础设施有限,新冠肺炎大流行在尼泊尔造成了前所未有的健康危机。缺乏足够的个人防护装备、标准化的检疫和隔离系统,实验室检测严重急性呼吸系统综合征冠状病毒2型的检测试剂盒不足,这在全国范围内造成了健康灾难。自从政府解除近四个月的封锁以来,新冠肺炎感染病例和死亡人数在尼泊尔飙升。为了识别感染SARS-CoV-2的人并防止疾病的进一步传播,诊断检测仍然至关重要。5目前,尼泊尔共有67个新冠肺炎指定诊断实验室,其中约三分之一来自私营部门。随着全国新感染病例的增加,大多数诊断实验室都面临试剂供应短缺、仪器使用短缺和人员需求增加的问题。因此,为检测而采集的拭子样本被堆积在实验室中,导致样本处理及其结果严重延迟。6,7这种情况进一步导致了居住在全国各地隔离中心的人们的沮丧、无聊和感染恐惧。持续的、前所未有的新冠肺炎疫情给尼泊尔的实验室服务和其他医疗干预领域带来了压力。尽管世界卫生组织认为各国有必要优先进行诊断检测以遏制冠状病毒的传播,但8尼泊尔政府没有进行足够的检测,同时缺乏基于科学证据的及时决定,更快地追踪接触者,从而防止疾病的进一步传播和传播。因此,尼泊尔政府应更加重视新冠肺炎的分子诊断技术,并使诊断设施在尼泊尔所有地区都能负担得起和使用。此外,为了限制持续疫情的社会经济和心理健康负担,9各州和联邦政府http://ijtmgh.comInt J Travel Med Glob Health。2020年11月;8(4):174-175 doi 10.34172/ijtmgh.2020.30 TMGH IInternational Journal of Travel Medicine and Global Health J
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