Prevalensi Kemampuan Mengecap Phenylthiocarbamide (PTC) Pada Penduduk Pulau Gili Ketapang Kabupaten Probolinggo

Abstract

The taste of sensitivity of phenylthiocarbamide (PTC), is autosomal dominant trait inherited. The taster controled by dominant allele while the non taster determinated by recessive allele. The purpose of the study is to investigate the prevalence of taster and non taster, gene frequencyof taster and non taster and pedegree analysis of non taster samples of Gili Ketapang island population in Probolinggo regency.. Determination of the sample was carry out randomly. Detection of the ability to taste PTC is done by asking respondents to feel the PTC solution. The PTC solution used was from the lowest concentration of 0.32mg/L (P13) to the highest concentration of 1300 mg/L (P1). The results showed that the prevalence of tasters and non-tasters were 96.88% and 3.12%, respectively. The non-taster (t) and taster (T) alleles frequencies were 0.17 and 0.83 respectively. The results of pedegree analysis show that non-taster are born from heterozygous taster pairs (husband and wife are Tt) or from heterozygous taster pairs (Tt) with non-taster (tt). Keyword: Phenylthiocarbamide (PTC), taster, non taster. Metamorfosa:Journal of Biological Sciences 10(1): 67-74 (Maret 2023) eISSN: 2655-8122