Surfao-cardio study: Trans-abdominal fetal ECG analysis in the second trimester of pregnancy in a cohort of healthy fetuses

IF 18 Q4 Medicine
M. Lachaud , R. Souriau , B. Rivet , J. Fontecave
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引用次数: 0

Abstract

Introduction

Although feasible with ultrasound, analysis of the fetal heart rhythm sometimes remains a challenge in the absence of access to the fetal electrocardiogram. In particular in case of suspected long QT, ultrasound does not allow the measurement of the ST segment.

Objective

Within the framework of the ANR SurFAO project, the Surfao-Cardio clinical study consisted in including 20 patients whose fetus did not present any cardiac morphological abnormality, between 22SA and 29SA. A trans-abdominal electrical recording was performed. The abdominal signals were formatted and processed to extract a fetal ECG. From the latter, measurements were made, automatically for RR intervals and manually for PR intervals.

These data were compared for each patient with ultrasound measurements in different modalities (M mode, Mitral-Aorta Profile, VCS-Aorta Doppler, Pulmonary Vein-Pulmonary Artery Doppler).

Results/Expected results

The fetal heart rate was analyzable in 12 of the 20 patients with a possible analysis of the QRS morphology for 12/12 patients and of the PR for 8/12 patients.

The correlations between the ultrasound data and the fetal ECG were respectively R = 0.79 (n = 12, P < 0.05) for heart rate and R = 0.81 (n = 8, P < 0.05) for PR intervals (Figure 1).

Conclusion/Perspectives

This preliminary study showed the feasibility of trans abdominal fetal ECG with good reliability of PR measurement. Some material limitations related to the recording of the trans-abdominal ECG were identified, giving hope for an improvement in the percentage of possible measurements and access to ST-segment measurement.

体表-心脏研究:一组健康胎儿妊娠中期经腹胎儿心电图分析
虽然超声是可行的,但在没有获得胎儿心电图的情况下,胎儿心律分析有时仍然是一个挑战。特别是在怀疑QT过长时,超声不允许测量ST段。目的在ANR SurFAO项目框架下,SurFAO - cardio临床研究包括20例胎儿在22SA至29SA之间未出现任何心脏形态异常的患者。经腹部电记录。腹部信号被格式化并处理以提取胎儿心电图。从后者进行测量,自动测量RR间隔,手动测量PR间隔。这些数据比较了每个患者在不同模式下的超声测量(M模式,二尖瓣-主动脉剖面图,vcs -主动脉多普勒,肺静脉-肺动脉多普勒)。结果/预期结果20例患者中12例可分析胎儿心率,12/12例可分析QRS形态学,8/12例可分析PR。超声资料与胎儿心电图的相关性R = 0.79 (n = 12, P <0.05), R = 0.81 (n = 8, P <结论/观点本初步研究表明经腹胎儿心电图测量PR的可行性和良好的可靠性。一些与经腹心电图记录有关的材料限制被确定,为可能测量的百分比和st段测量的获得提供了希望。
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来源期刊
Archives of Cardiovascular Diseases Supplements
Archives of Cardiovascular Diseases Supplements CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
0.00%
发文量
508
期刊介绍: Archives of Cardiovascular Diseases Supplements is the official journal of the French Society of Cardiology. The journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles, editorials, and Images in cardiovascular medicine. The topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Additionally, Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.
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