Periodontal manifestations as related to the cytokines in the gingival crevicular fluid

Abstract

Backround: Periodontal diseases are classified into different categories based on the clinical symptoms and related to these there can be changes in the cytokine levels in the connective tissue and elaboration of these in the gingival crevicular fluid. (GCF). Aims and objectives: The aim of this study was to evaluate the levels of IL-11 and IL-17 in the gingival crevicular fluid of patients with Aggressive Periodontitis and Chronic Periodontitis and co-relate them with the clinical parameters. Materials and Methods: GCF was collected from the deepest sites of the periodontitis patients and ELIS A was used to determine the levels of IL-11 and IL-17 levels. Results: GCF of patients in each category was assayed and the levels of IL-11 and IL-17 were co-related with clinical symptoms. Conclusion: Study showed strong co-relation of Aggressive and Chronic Periodontitis with IL-11 and IL-17.