Functional Constipation Frequency in Children Diagnosed with Autism Spectrum Disorder

Çağatay Günay, H. Civan, Semra Yılmaz, Didem Taskin
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Abstract

Aim: In our study, we aimed to determine the frequency of functional constipation in children diagnosed with autism spectrum disorders by child and adolescent psychiatry and mental health.Materials and Methods: Between September 2017 and September 2018, children with autism spectrum disorder who applied to BakırköySadiKonuk Education and Research Hospital Child and Adolescent Psychiatry Outpatient Clinic were evaluated by means of childhood autism rating scale (CARS). A total of 108 patients were evaluated with the Roman IV criteria and the frequency of functional constipation was investigated.Results: A total of 108 cases, 87% (n = 94) male and 13% (n = 14) female, were studied. The ages of the patients were between 2 and 15 years and the mean age was 6.89 ± 2.76. Organic constipation was not detected in patients with constipation and all of them were diagnosed as functional constipation. There was no statistically significant difference between the rates of functional constipation in cases according to gender. The incidence of functional constipation in males was significantly higher in patients with severe autism than in those with mild to moderate autism. “Two or fewer defecations in the toilet per week” criteria was found significantly higher in girls than in boys. No significant difference was found for the other five criteria according to gender. Each of the six criteria of the Rome IV criteria were found to be significantly higher in patients with severe autism than those with mild to moderate autism according to CARS scores. One of the Roman IV criteria, “History of large diameter stools that may obstruct the toilet” was found significantly higher in patients aged nine years and older. No significant correlation was found between the other criteria and age groups.Conclusion: All of the six criteria of the Roman IV criteria were significantly higher in cases with severe autism according to CARS, compared to those with mild to moderate autism.
自闭症谱系障碍患儿功能性便秘的发生率
目的:在我们的研究中,我们旨在确定通过儿童和青少年精神病学和心理健康诊断为自闭症谱系障碍的儿童功能性便秘的频率。材料和方法:2017年9月至2018年9月,采用儿童自闭症评定量表(CARS)对申请BakırköySadiKonuk教育研究医院儿童和青少年精神病学门诊的自闭症谱系障碍儿童进行评估。共有108名患者采用Roman IV标准进行了评估,并对功能性便秘的频率进行了调查。结果:共108例,其中87%(n=94)为男性,13%(n=14)为女性。患者年龄在2至15岁之间,平均年龄为6.89±2.76岁。便秘患者未发现器质性便秘,均诊断为功能性便秘。在不同性别的病例中,功能性便秘的发生率之间没有统计学上的显著差异。重度自闭症患者男性功能性便秘的发生率明显高于轻度至中度自闭症患者。“每周在厕所排便两次或更少”的标准在女孩中明显高于男孩。根据性别,其他五项标准没有发现显著差异。根据CARS评分,罗马IV标准的六项标准中的每一项在严重自闭症患者中都明显高于轻度至中度自闭症患者。罗马IV标准之一“可能堵塞厕所的大直径大便史”在9岁及以上的患者中发现明显更高。在其他标准和年龄组之间没有发现显著的相关性。结论:根据CARS,与轻度至中度自闭症患者相比,严重自闭症患者的Roman IV标准的所有六项标准均显著较高。
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