Effect of different grades of corpus luteum blood flow on conservative treatment in patients with unruptured tubal pregnancy

中国综合临床 Pub Date : 2019-07-01 DOI:10.3760/CMA.J.ISSN.1008-6315.2019.04.017

X. Song

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Abstract

Objective To study the effect of different grades of corpus luteum blood flow on conservative treatment of unruptured tubal pregnancy. Methods One hundred and fifty-six patients who were diagnosed with unruptured tubal pregnancy in the General Hospital of Northern War Zone and accepted conservative treatment from February 2013 to February 2018 were retrospectively analyzed.The patients were divided into corpus luteum blood level 0 group(0 grade group, 36 cases), corpus luteum blood level 1 group(1 grade group, 41 cases), corpus luteum blood level 2 group(2 grade group, 45 cases), corpus luteum blood level 3 group(3 grade group, 34 cases)according to the corpus luteum blood flow classification in pregnancy.The levels of blood β-HCG, the packet reducing and the curative effect were compared among the four groups. Results The time ofβ-HCG decreased to normal after treatment in 0~3 grade group was (14.4±2.7) d, (16.2±3.9) d, (23.3±4.8) d, (27.0±4.6) d respectively, there was significant difference among the four groups (F=5.338, P=0.039). The time of mass disappeared completely after treatment in 0-3 grade group was (13.2±2.2)d, (15.9±3.0)d, (21.8±2.9)d, (24.1±3.4)d respectively, there was significant difference among the four groups (F=4.229, P=0.043). The curative rate in 0-3 grade group was 91.7%(33/36), 87.8%(36/41), 82.2%(37/45), 73.5%(25/34) respectively, there was significant difference among the four groups(χ2=4.586, P=0.041). There was no significant difference in incidence of adverse reactions among the four groups (P>0.05). Conclusion The different classification of corpus luteum blood flow in pregnancy of unruptured tubal pregnancy have significant influence on the conservative treatment effect.The higher the blood flow classification, the longer treatment time and the worse the curative effect. Key words: Tubal pregnancy; Corpus luteum of pregnancy; Blood flow classification; Conservative treatment

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不同级别黄体血流对未破裂输卵管妊娠患者保守治疗的影响

目的探讨不同级别黄体血流对未破裂输卵管妊娠保守治疗的影响。方法对2013年2月至2018年2月在北部战区总医院诊断为未破裂输卵管妊娠并接受保守治疗的156例患者进行回顾性分析。根据妊娠期黄体血流量分类，将患者分为黄体血流量0组（0级组，36例）、黄体血流量1组（1级组，41例）、卵泡血流量2组（2级组，45例）和黄体血流量3组（3级组，34例）。比较四组患者的血β-HCG水平、降压效果及疗效。结果0～3级组治疗后β-HCG降至正常的时间分别为（14.4±2.7）d、（16.2±3.9）d，（23.3±4.8）d，和（27.0±4.6）d，四组间有显著性差异（F=5.338，P=0.039），0～3级别组治疗后肿块完全消失的时间分别是（13.2±2.2）d，0-3级组治愈率分别为91.7%（33/36）、87.8%（36/41）、82.2%（37/45）、73.5%（25/34），4组间差异有统计学意义（χ2=4.586，P=0.041），不良反应发生率差异无统计学意义（P>0.05）。血流量分级越高，治疗时间越长，疗效越差。关键词：输卵管妊娠；妊娠黄体；血流分类；保守治疗

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来源期刊

中国综合临床

CiteScore

0.10

自引率

0.00%

发文量

16855

期刊介绍： Clinical Medicine of China is an academic journal organized by the Chinese Medical Association (CMA), which mainly publishes original research papers, reviews and commentaries in the field. Clinical Medicine of China is a source journal of Peking University (2000 and 2004 editions), a core journal of Chinese science and technology, an academic journal of RCCSE China Core (Extended Edition), and has been published in Chemical Abstracts of the United States (CA), Abstracts Journal of Russia (AJ), Chinese Core Journals (Selection) Database, Chinese Science and Technology Materials Directory, Wanfang Database, China Academic Journal Database, JST Japan Science and Technology Agency Database (Japanese) (2018) and other databases.