The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database

IF 1.6 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
M. Protty, S. Gallagher, Andrew S P Sharp, V. Farooq, M. Egred, P. O'Kane, P. Ludman, M. Mamas, T. Kinnaird
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引用次数: 0

Abstract

Introduction There is increasing evidence supporting the use of intracoronary imaging to optimize the outcomes of percutaneous coronary intervention (PCI). However, there are no studies examining the impact of imaging on PCI outcomes in cases utilising rotational atherectomy (RA-PCI). Our study examines the determinants and outcomes of using intracoronary imaging in RA-PCI cases including 12-month mortality. Methods Using the British Cardiac Intervention Society database, data were analysed on all RA-PCI procedures in the UK between 2007 and 2014. Descriptive statistics and multivariate logistic regressions were used to examine baseline, procedural, and outcome associations with intravascular imaging. Results Intracoronary imaging was used in 1,279 out of 8,417 RA-PCI cases (15.2%). Baseline covariates associated with significantly more imaging use were number of stents used, smoking history, previous CABG, pressure wire use, proximal LAD disease, laser use, glycoprotein inhibitor use, cutting balloons, number of restenosis attempted, off-site surgery, and unprotected left main stem (uLMS) PCI. Adjusted rates of in-hospital major adverse cardiac/cerebrovascular events (IH-MACCE), its individual components (death, peri-procedural MI, stroke, and major bleed), or 12-month mortality were not significantly altered by the use of imaging in RA-PCI. However, subgroup analysis demonstrated a signal towards reduction in 12-month mortality in uLMS RA-PCI cases utilising intracoronary imaging (OR 0.67, 95% CI 0.44–1.03). Conclusions Intracoronary imaging use during RA-PCI is associated with higher risk of baseline and procedural characteristics. There were no differences observed in IH-MACCE or 12-month mortality with intracoronary imaging in RA-PCI.
冠状动脉内成像对旋转动脉粥样硬化切除术患者PCI结果的影响:英国心血管干预学会数据库中8417例旋转动脉粥样硬化切除病例的分析
引言越来越多的证据支持使用冠状动脉内成像来优化经皮冠状动脉介入治疗(PCI)的结果。然而,没有研究检查在使用旋磨术(RA-PCI)的病例中成像对PCI结果的影响。我们的研究检查了在RA-PCI病例中使用冠状动脉内成像的决定因素和结果,包括12个月的死亡率。方法使用英国心脏干预学会数据库,分析2007年至2014年间英国所有RA-PCI手术的数据。描述性统计和多变量逻辑回归用于检查基线、程序和结果与血管内成像的相关性。结果8417例RA-PCI患者中1279例(15.2%)使用了冠状动脉内成像。与显著增加成像使用相关的基线协变量为支架使用次数、吸烟史、既往冠状动脉旁路移植术、压力线使用、近端LAD疾病、激光使用、糖蛋白抑制剂使用、切割球囊、尝试再狭窄次数、场外手术,以及无保护的左主干(uLMS)PCI。在RA-PCI中使用成像并没有显著改变院内主要不良心脑血管事件(IH-MACCE)、其单个组成部分(死亡、围手术期MI、中风和大出血)或12个月死亡率的调整率。然而,亚组分析表明,在使用冠状动脉内成像的uLMS RA-PCI病例中,有降低12个月死亡率的信号(OR 0.67,95%CI 0.44-1.03)。结论在RA-PCI期间使用冠状动脉成像与基线和手术特征的较高风险相关。RA-PCI冠状动脉内成像在IH-MACCE或12个月死亡率方面没有观察到差异。
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来源期刊
Journal of interventional cardiology
Journal of interventional cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.80
自引率
0.00%
发文量
81
审稿时长
6-12 weeks
期刊介绍: Journal of Interventional Cardiology is a peer-reviewed, Open Access journal that provides a forum for cardiologists determined to stay current in the diagnosis, investigation, and management of patients with cardiovascular disease and its associated complications. The journal publishes original research articles, review articles, and clinical studies focusing on new procedures and techniques in all major subject areas in the field, including: Acute coronary syndrome Coronary disease Congenital heart diseases Myocardial infarction Peripheral arterial disease Valvular heart disease Cardiac hemodynamics and physiology Haemostasis and thrombosis
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