D. Scheunemann, A. Pradhan, Swadesh K. Das, D. Sarkar, L. Emdad, P. Fisher
{"title":"Wnt7a and miR-370-3p: new contributors to bladder cancer invasion.","authors":"D. Scheunemann, A. Pradhan, Swadesh K. Das, D. Sarkar, L. Emdad, P. Fisher","doi":"10.21037/BIOTARGET.2018.08.02","DOIUrl":null,"url":null,"abstract":"In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.","PeriodicalId":92338,"journal":{"name":"Biotarget","volume":"2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/BIOTARGET.2018.08.02","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotarget","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/BIOTARGET.2018.08.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.