Antibacterial Properties and Flavonoids Content of Some Mosses Common in Armenia

Q4 Pharmacology, Toxicology and Pharmaceutics

Iranian Journal of Pharmaceutical Sciences Pub Date : 2021-10-01 DOI:10.22034/IJPS.2020.121318.1639

I. Semerjyan, G. Semerjyan, H. Semerjyan, A. Trchounian

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引用次数: 2

Abstract

The present study was aimed to evaluate the antibacterial potential of ethanol, methanol, acetone and aqueous extracts of some bryophytes common in Armenia (Mnium spinosum (Voit) Schwaegr, Brachythecium salebrosum (Web. et Mohr) B.S.G., Thuidiumrecognitum (Hedw) Lindb and Dicranum scoparium (Hedw). Antibacterial activity was determined using agar-well diffusion method against five bacterial species (Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Salmonella enterica and S. typhimirium). The results showed that the bryophytes D. scoparium and B. salebrosum possessed high antibacterial activity in methanol extracts, whereas M. spinosum - in acetone extract. Antibacterial activity against S. aureus was comparably weaker. Ethanol extract of T. recognitum had greater antibacterial activity than the extract of M. spinosum. Of all those tested for antibacterial activity bryophytes in vitro extracts of D. scoparium have yielded the most promising results. Antibacterial activity might be caused by a high content of flavonoids in bryophytes determined. Thus, the studied bryophytes might be used to develop new antibacterial agents.

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亚美尼亚常见藓类植物的抗菌性能及类黄酮含量

本研究旨在评价亚美尼亚常见苔藓植物(um spinosum (Voit) Schwaegr, Brachythecium salebrosum (Web.)， Brachythecium salebrosum)的乙醇、甲醇、丙酮和水提取物的抑菌潜力。等Mohr) B.S.G, Thuidiumrecognitum (Hedw) Lindb和Dicranum scoparium (Hedw)。采用琼脂孔扩散法测定对大肠杆菌、枯草芽孢杆菌、金黄色葡萄球菌、肠炎沙门氏菌和鼠伤寒沙门氏菌5种细菌的抑菌活性。结果表明，在甲醇提取物中，苔藓植物东莨菪和龙葵具有较高的抑菌活性，而在丙酮提取物中，棘草具有较高的抑菌活性。对金黄色葡萄球菌的抑菌活性相对较弱。金针菇乙醇提取物的抑菌活性高于棘毛菌提取物。在所有对苔藓植物抑菌活性进行的测试中，东莨菪提取物获得了最有希望的结果。苔藓植物中黄酮类化合物的高含量可能是其抗菌活性的主要原因。因此，所研究的苔藓植物可用于开发新的抗菌药物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： Iranian Journal of Pharmaceutical Sciences (IJPS) is an open access, internationally peer-reviewed journal that seeks to publish research articles in different pharmaceutical sciences subdivisions: pharmacology and toxicology, nanotechnology, pharmaceutics, natural products, biotechnology, pharmaceutical chemistry, clinical pharmacy and other pharmacy related topics. Each issue of the journal contents 16 outstanding research articles in area of pharmaceutical sciences plus an editorial written by the IJPS editors on one of the most up to date advances topics in pharmacy. All articles published by IJPS would be permanently accessible online freely without any subscription charges. Authors of the published articles have granted the right to use and disseminate their article to third parties.