Multifocal Tuberculosis Presenting as Mandibular Swelling in a 3-Year-Old Boy: A Case Report

Kathleen Kay Yambot, Neil Aldrine Peñaflor
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Abstract

ABSTRACTObjective: To report a case of multifocal pediatric tuberculosis presenting with mandibular swelling and discuss its etiology, clinical findings, diagnosis, management, and outcome after treatment. Methods: Design: Case Report Setting: Tertiary Government Training Hospital Patient: One Results: A 3-year-old boy presented with progressive non-tender, right mandibular swelling for 11 months. Panoramic X-ray exhibited extensive multiple loculations with lytic changes on the mandible. CT Scans revealed a peripherally enhancing hypodense mass with lytic expansion of the right mandibular angle extending across the left mandibular body with an incidental finding of right lung mass. Other extrapulmonary lesions were also detected involving the scapula, pleura with lysis of the adjacent ribs at the level of T7 and T8. Biopsy of the mandibular and lung mass confirmed the presence of caseating and non-caseating granulomas consistent with Koch’s infection. The patient showed significant improvement by the 7th month of a 12-month course of anti-tuberculous therapy. Conclusion: Multifocal TB can present as simple mandibular swelling, and a thorough workup should look for other involved sites. Early diagnosis in children may prevent debilitating sequelae and improve long-term treatment outcomes.
多灶性结核表现为3岁男孩下颌骨肿胀1例
摘要:目的:报告1例以下颌骨肿胀为临床表现的多灶性儿童结核,并讨论其病因、临床表现、诊断、处理和治疗后的结果。方法:设计:病例报告设置:三级政府培训医院患者:1例结果:1例3岁男童,表现为进行性无压痛性右下颌肿胀11个月。全景x线显示下颌骨广泛的多位置和溶解性改变。CT扫描显示一个周围增强的低密度肿块,右下颌骨角溶解性扩张,延伸到左下颌骨体,偶然发现右肺肿块。其他肺外病变也被发现累及肩胛骨、胸膜,并在T7和T8水平附近的肋骨溶解。下颌骨和肺部肿块的活检证实了干酪化和非干酪化肉芽肿的存在,与Koch感染一致。在12个月的抗结核治疗的第7个月,患者表现出明显的改善。结论:多灶性结核可表现为单纯的下颌骨肿胀,应仔细检查其他受累部位。儿童早期诊断可预防衰弱后遗症并改善长期治疗结果。
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