Três casos de miosite induzida pelo anti‐TNF e revisão da literatura

Q Medicine
Orhan Zengin , Mustafa Erkut Onder , Samet Alkan , Gezmiş Kimyon , Nergis Hüseynova , Zeynep Hanım Demir , Bünyamin Kısacık , Ahmet Mesut Onat
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引用次数: 11

Abstract

Anti‐tumor necrosis factor (anti‐TNF) drugs are frequently preferred in the treatment of rheumatologic diseases and other inflammatory diseases. The development of myositis after using anti‐TNF is a rare clinical condition. Here we aimed to report cases who developed myositis after using anti‐TNF and review the current literature. We report two cases of rheumatoid arthritis (RA) and a case of ankylosing spondylitis (AS) developed idiopathic inflammatory myopathy following anti‐TNF therapy. In conclusion, myositis could develop during anti‐TNF therapy, so these patients should be evaluated carefully initially for myositis and should be closely monitored due to the potential for developing myositis in treatment process.

抗TNF诱导的肌炎3例并文献复习
抗肿瘤坏死因子(Anti - TNF)药物通常是治疗风湿病和其他炎症性疾病的首选药物。使用抗肿瘤坏死因子后发生肌炎是一种罕见的临床情况。在这里,我们的目的是报告使用抗肿瘤坏死因子后发生肌炎的病例,并回顾目前的文献。我们报告2例类风湿性关节炎(RA)和1例强直性脊柱炎(AS)在抗TNF治疗后发展为特发性炎性肌病。总之,在抗肿瘤坏死因子治疗期间可能发生肌炎,因此这些患者应在最初仔细评估肌炎,并应密切监测,因为在治疗过程中可能发生肌炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.82
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: RBR nasceu da necessidade de se criar um órgão oficial da SBR que pudesse divulgar a produção científica dos reumatologistas brasileiros. O primeiro número foi publicado em setembro de 1957. A partir do volume 18 (1978), passou a seis números, com periodicidade atual. A RBR, em sua trajetória, tem sido objeto de constantes mudanças, sempre visando ao seu aprimoramento e revitalização, tanto em sua apresentação como em seu conteúdo.
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