Role of High-sensitivity Cardiac Troponin in Acute Coronary Syndrome

Q4 Medicine

US Cardiology Review Pub Date : 2018-11-04 DOI:10.15420/USC.2018.16.1

M. Narayanan, S. Garcia

引用次数: 2

Abstract

Chest pain is one of the most common reasons for an emergency room (ER) visit in the US, with almost 6 million ER visits annually. High-sensitivity cardiac troponin (hscTn) assays have the ability to rapidly rule in or rule out acute coronary syndrome with improved sensitivity, and they are increasingly being used. Though hscTn assays have been approved for use in European, Australian, and Canadian guidelines since 2010, the FDA only approved their use in 2017. There is no consensus on how to compare the results from various hscTn assays. A literature review was performed to analyze the advantages and limitations of using hscTn as a standard biomarker to evaluate patients with suspected ACS in the emergency setting.

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高敏感性心肌肌钙蛋白在急性冠脉综合征中的作用

胸痛是美国急诊室就诊最常见的原因之一，每年有近600万人次急诊就诊。高灵敏度心肌肌钙蛋白（hscTn）检测具有快速排除或排除急性冠状动脉综合征的能力，灵敏度有所提高，并且越来越多地被使用。尽管自2010年以来，hscTn检测已被欧洲、澳大利亚和加拿大的指南批准使用，但美国食品药品监督管理局直到2017年才批准使用。关于如何比较各种hscTn测定的结果，目前还没有达成共识。对文献进行了回顾，以分析在急诊环境中使用hscTn作为标准生物标志物来评估疑似ACS患者的优势和局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

US Cardiology Review Medicine-Cardiology and Cardiovascular Medicine

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： US Cardiology Review (USC) is an international, US-English language, peer-reviewed journal that is published bi-annually and aims to assist time-pressured physicians to stay abreast of key advances and opinion in the area of cardiovascular disease. The journal comprises balanced and comprehensive review articles written by leading authorities. The journal provides updates on a range of salient issues to support physicians in developing their knowledge and effectiveness in day-to-day clinical practice. The journal endeavours to support the continuous medical education of specialist and general cardiologists and disseminate knowledge of the field to the wider cardiovascular community.