Pulmonary Vascular Resistance (PVR) Late after Heart Transplant in Patients with Higher Preoperative Pulmonary Hypertension and Influence on Survival-A Study from India

Abstract

We studied 12 Patients who underwent Successful heart Transplant with High Pre-operative Pulmonary pressures – defined as PA systolic pressure more than 50 mm Hg but with Transpulmonary Gradient less than 16 mm hg after Vasodilator testing, for analysis of Pulmonary heamodynamic parameters like Pulmonary Vascular Resistance, (PVR) and Pulmonary Compliance(Pca) early (one month) and one Year after Heart Transplantation along with Survival at 6 months and one year. These 12 patients were statistically compared with 25 patients who had preoperative PA systolic pressures less than 50mm hg 11 of above patients were on both Sildenefil and Ambrisentan for PAH [1].