[Atypical fibroxanthoma].

Q4 Medicine

Arkhiv patologii Pub Date : 2023-01-01 DOI:10.17116/patol20238505165

N V Vasilyev, S V Vtorushin, A A Maltseva, A V Sannikova

引用次数: 0

Abstract

Atypical fibroxanthoma (AFX) is a rare skin tumor characterized by a combination of a «malignant» morphological features and non-aggressive clinical course. Diagnosing AFX is challenging due to histological «diversity» and heterogeneous immunophenotype. The presented review describes the history and evolution of AFX as a nosological form of cancer, its histogenetic origin, pathogenesis and biological potential. The clinical, morphological, immunohistochemical, molecular cytogenetic characteristics and histological subtypes of the tumor as well as differential diagnosis have been presented in detail.

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[非典型纤维黄色瘤]。

非典型纤维黄色瘤（AFX）是一种罕见的皮肤肿瘤，其特征是具有“恶性”形态学特征和非侵袭性临床过程。由于组织学“多样性”和异质性免疫表型，诊断AFX具有挑战性。本文综述了AFX作为癌症的一种病理形式的历史和演变、其组织遗传学起源、发病机制和生物学潜力。详细介绍了肿瘤的临床、形态学、免疫组织化学、分子细胞遗传学特征、组织学亚型以及鉴别诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arkhiv patologii Medicine-Pathology and Forensic Medicine

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.