Uncovering the effects of COVID-19 on in-hospital cardiac arrest - a living systematic review and meta-analysis.

IF 1.3 4区医学 Q4 ENVIRONMENTAL SCIENCES

Annals of Agricultural and Environmental Medicine Pub Date : 2023-09-28 Epub Date: 2023-06-16 DOI:10.26444/aaem/166757

Karol Bielski, Michal Pruc, Zubaid Rafique, Frank William Peacock, Jaroslaw Chmielewski, Lech Panasiuk, Lukasz Szarpak, Nicola Luigi Bragazzi, Izabela Chojnowska-Ćwiąkała

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引用次数: 0

Abstract

Introduction and objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic and had a negative impact on the entire health care system. To understand the effect of COVID-19 on outcomes of in-hospital cardiac arrest (IHCA), a systematic review and meta-analysis of studies was designed to compare the pre- and intra-pandemic periods of adult patients who suffered cardiac arrest, and additionally by performing a sub-analysis related to COVID-19 positive vs. negative patients in the same group of patients.

Material and methods: To evaluate the impact of COVID-19 on IHCA outcomes a systematic review and meta-analysis was performed. Pubmed (MEDLINE), Scopus, Embase, Web of Science, and Cochrane database were searched for articles published from 1 January 2020 - 8 April 2023.

Results: Return of spontaneous circulation events among IHCA patients in pre-COVID-19 and COVID-19 pandemic periods varied and amounted to 64.0% vs. 60.0%, respectively (OR=1.23; 95%CI: 1.19 to 1.26; p<0.001). Re-arrest occurrence was 4.5% vs. 4.9%, respectively (OR=1.24; 95%CI: 1.00 to 1.53; p=0.05). Survival to hospital discharge (SHD) was 25.1% compared to 20.9% for COVID-19 period (OR = 1.17; 95%CI: 0.96 to 1.41; p=0.12). During the COVID-19 period, SHD in COVID-19 positive patients was 14.0% compared to 25.9% for patients without COVID-19 (OR=0.72; 95%CI: 0.28 to 1.86; p=0.50). 30-day survival rate among COVID-19 positive vs. negative patients was 62.6% vs. 58.3%, respectively (OR =0.99; 95%CI: 0.23 to 4.24; p=0.99).

Conclusions: Patients with SARS-CoV-2 infection had reduced rates of ROSC and SDH, as well as poorer neurologic outcomes and increased in hospital re-arrests during the COVID-19 period. However, the 30-day survival rate was similar in SARS-CoV-2 positive and negative patients.

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揭示新冠肺炎对住院心脏骤停的影响——一项活的系统综述和荟萃分析。

引言和目的：严重急性呼吸综合征冠状病毒2型（严重急性呼吸系统综合征冠状病毒）引起了一场全球大流行，并对整个医疗保健系统产生了负面影响。为了了解新冠肺炎对院内心脏骤停（IHCA）结果的影响，设计了一项研究的系统回顾和荟萃分析，以比较心脏骤停成年患者的发病前和发病期，并对同一组患者中的新冠肺炎阳性与阴性患者进行亚分析。材料和方法：为了评估新冠肺炎对IHCA结果的影响，进行了系统回顾和荟萃分析。检索Pubmed（MEDLINE）、Scopus、Embase、Web of Science和Cochrane数据库中2020年1月1日至2023年4月8日发表的文章，分别为（OR=1.23；95%CI:1.19至1.26；P结论：在新冠肺炎期间，SARS-CoV-2感染患者的ROSC和SDH发生率降低，神经系统结果较差，住院死亡率增加。然而，SARS-CoV-2阳性和阴性患者的30天生存率相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Agricultural and Environmental Medicine 医学-公共卫生、环境卫生与职业卫生

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

4-8 weeks

期刊介绍： All papers within the scope indicated by the following sections of the journal may be submitted: Biological agents posing occupational risk in agriculture, forestry, food industry and wood industry and diseases caused by these agents (zoonoses, allergic and immunotoxic diseases). Health effects of chemical pollutants in agricultural areas , including occupational and non-occupational effects of agricultural chemicals (pesticides, fertilizers) and effects of industrial disposal (heavy metals, sulphur, etc.) contaminating the atmosphere, soil and water. Exposure to physical hazards associated with the use of machinery in agriculture and forestry: noise, vibration, dust. Prevention of occupational diseases in agriculture, forestry, food industry and wood industry. Work-related accidents and injuries in agriculture, forestry, food industry and wood industry: incidence, causes, social aspects and prevention. State of the health of rural communities depending on various factors: social factors, accessibility of medical care, etc.