[Metallic mercury poisoning caused by intravenous injection in vague circumstances--a case report].

Przeglad lekarski Pub Date : 2012-01-01
Anna Bazylewicz, Tomasz Kłopotowski, Mariusz Kicka, Łukasz Miśkiewicz, Sebastian Picheta
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Abstract

Unlabelled: Mercury is a heavy metal found in nature in three forms: metallic mercury, organic and inorganic compounds. It is a general protoplasmatic toxin. The pathophysiology of mercury toxicity is related to its binding to sulfhydryl groups of different receptor proteins and cellular enzymes, interrupting cellular metabolism and in this way causing cell death. In the paper we present a case of 57-year-old woman, who was admitted due to suspicion of metallic mercury parenteral poisoning. The computed tomography (CT) scan of abdomen accidentally revealed multiple disseminated tiny metallic densities. The blood mercury level was high (41.9 microg/l), as well as mercury urine level (85.7 microg/g creatinine which was 42.8 microg/l). Neurologic examination revealed unobtrusive symptoms of cerebellum affection. Psychological examination revealed disturbances of cognitive abilities reliant on the efficiency of vision organ. The results of A. Benton's organic test were abnormal. Psychiatric examination revealed no abnormalities. Results of pulmonary function tests were within normal limits.

Conclusions: The intravenous injection of metallic mercury did not cause serious clinical effects. Followup examination in order to reveal chronic toxic effects is necessary. Diagnostics and treatment of metallic mercury intoxications by parenteral injection should be carried out in the clinical toxicology departments.

[模糊情况下静脉注射致金属汞中毒一例报告]。
未标记:汞是一种重金属,在自然界中有三种形式:金属汞、有机化合物和无机化合物。它是一种一般的原生质体毒素。汞毒性的病理生理学与汞与不同受体蛋白和细胞酶的巯基结合有关,干扰细胞代谢,从而导致细胞死亡。在本文中,我们介绍了一例57岁的妇女,她因怀疑金属汞肠外中毒而入院。腹部计算机断层扫描意外发现多个弥散性微小金属密度。血汞水平高(41.9微克/升),尿汞水平(85.7微克/克肌酸酐,即42.8微克/升。神经系统检查显示小脑病变症状不明显。心理检查显示认知能力的紊乱依赖于视觉器官的效率。A.Benton的有机物测试结果异常。精神检查没有发现异常。肺功能测试结果在正常范围内。结论:静脉注射金属汞未引起严重的临床疗效。为了揭示慢性毒性作用,有必要进行随访检查。金属汞中毒的胃肠外注射诊断和治疗应在临床毒理学部门进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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