Periosteal chondroblastoma of the femoral neck: two cases and a review of the literature.

IF 1.9 3区医学 Q2 ORTHOPEDICS

Skeletal Radiology Pub Date : 2024-05-01 Epub Date: 2023-09-21 DOI:10.1007/s00256-023-04440-2

Clovis Guillois, Sisi Yang, David Biau, Antoine Feydy, Frédérique Larousserie

引用次数: 0

Abstract

Chondroblastoma is a rare benign cartilaginous tumor mostly confined to the epiphyses and apophyses. Cases outside the epiphyseal region are exceedingly rare. Extramedullary chondroblastomas are exceptional; to our knowledge, only two cases qualified as "periosteal chondroblastoma" have been described in the literature. We report two cases of metaphyseal periosteal chondroblastoma both located on the inferior surface of the femoral neck. Both cases were paucicellular with an unusual dense sclerotic reaction. The diagnosis of chondroblastoma was supported by the expression of histone 3.3, K36M mutant in tumor cells.

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股骨颈骨膜软骨母细胞瘤：两例并文献复习。

软骨母细胞瘤是一种罕见的良性软骨肿瘤，主要局限于骨骺和骨突。骨骺区以外的病例极为罕见。髓外软骨母细胞瘤是例外；据我们所知，文献中仅描述了两例符合“骨膜软骨母细胞瘤”的病例。我们报告两例均位于股骨颈下表面的干骺端骨膜软骨母细胞瘤。这两个病例都是少细胞的，有一种不寻常的致密硬化反应。组蛋白3.3、K36M突变体在肿瘤细胞中的表达支持了软骨母细胞瘤的诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Skeletal Radiology 医学-核医学

CiteScore

4.40

自引率

9.50%

发文量

253

审稿时长

3-8 weeks

期刊介绍： Skeletal Radiology provides a forum for the dissemination of current knowledge and information dealing with disorders of the musculoskeletal system including the spine. While emphasizing the radiological aspects of the many varied skeletal abnormalities, the journal also adopts an interdisciplinary approach, reflecting the membership of the International Skeletal Society. Thus, the anatomical, pathological, physiological, clinical, metabolic and epidemiological aspects of the many entities affecting the skeleton receive appropriate consideration. This is the Journal of the International Skeletal Society and the Official Journal of the Society of Skeletal Radiology and the Australasian Musculoskelelal Imaging Group.