The Guiding Significance of Fractional Flow Reserve (FFR) for Coronary Heart Disease Revascularization.

IF 2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Discovery medicine Pub Date : 2021-01-01
Maodong Yang, Li Zhang, Han Tang, Dechang Zheng, Jian Wu
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引用次数: 0

Abstract

Coronary angiography is an important diagnostic tool for coronary heart disease. While it can identify anatomical coronary stenosis, its ability to identify hemodynamic changes is limited. The Fractional Flow Reserve (FFR) technique, combined with coronary angiography, facilitates both the functional and anatomical assessment of heart disease. New studies have shown that FFR has unique advantages in guiding percutaneous coronary intervention (PCI), and it is currently being used in coronary artery bypass graft (CABG) as well as for assessing the prognosis of patients after surgery. It may also play a significant role in assessing the patency of a graft. However, some studies have shown that in considering the cardioprotective benefits of CABG, applying FFR guidelines to CABG may reduce or impair its "surgical collateralization" effect and increase the rate of incomplete revascularization. We compared the advantages and disadvantages of FFR to guide PCI and CABG, which will provide health practitioners with useful resources to determine the best diagnosis and treatment for patients.

血流储备分数(FFR)对冠心病血运重建的指导意义。
冠状动脉造影是诊断冠心病的重要工具。虽然它可以识别解剖冠状动脉狭窄,但其识别血流动力学变化的能力有限。分数血流储备(FFR)技术与冠状动脉造影相结合,有助于心脏疾病的功能和解剖评估。新的研究表明,FFR在引导经皮冠状动脉介入治疗(PCI)方面具有独特的优势,目前正被用于冠状动脉旁路移植术(CABG)以及评估患者术后预后。它也可能在评估移植物通畅方面发挥重要作用。然而,一些研究表明,考虑到冠状动脉搭桥的心脏保护作用,将FFR指南应用于冠状动脉搭桥可能会降低或损害其“手术侧支”作用,并增加不完全血运重建的发生率。我们比较了FFR的优缺点来指导PCI和CABG,这将为医疗从业者确定患者的最佳诊断和治疗提供有用的资源。
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来源期刊
Discovery medicine
Discovery medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.40
自引率
0.00%
发文量
80
审稿时长
6-12 weeks
期刊介绍: Discovery Medicine publishes novel, provocative ideas and research findings that challenge conventional notions about disease mechanisms, diagnosis, treatment, or any of the life sciences subjects. It publishes cutting-edge, reliable, and authoritative information in all branches of life sciences but primarily in the following areas: Novel therapies and diagnostics (approved or experimental); innovative ideas, research technologies, and translational research that will give rise to the next generation of new drugs and therapies; breakthrough understanding of mechanism of disease, biology, and physiology; and commercialization of biomedical discoveries pertaining to the development of new drugs, therapies, medical devices, and research technology.
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