Effectiveness of a Novel Contralaterally Controlled Neuromuscular Electrical Stimulation for Restoring Lower Limb Motor Performance and Activities of Daily Living in Stroke Survivors: A Randomized Controlled Trial.

IF 4.3 3区材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC

ACS Applied Electronic Materials Pub Date : 2022-01-11 eCollection Date: 2022-01-01 DOI:10.1155/2022/5771634

Ying Shen, Lan Chen, Li Zhang, Shugang Hu, Bin Su, Huaide Qiu, Xingjun Xu, Guilan Huang, Zhifei Yin, Jinyu Yang, Chuan Guo, Tong Wang

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引用次数: 4

Abstract

Background: Contralaterally controlled neuromuscular electrical stimulation (CCNMES) is a novel electrical stimulation treatment for stroke; however, reports on the efficacy of CCNMES on lower extremity function after stroke are scarce.

Objective: To compare the effects of CCNMES versus NMES on lower extremity function and activities of daily living (ADL) in subacute stroke patients.

Methods: Forty-four patients with a history of subacute stroke were randomly assigned to a CCNMES group and a NMES group (n = 22 per group). Twenty-one patients in each group completed the study per protocol, with one subject lost in follow-up in each group. The CCNMES group received CCNMES to the tibialis anterior (TA) and the peroneus longus and brevis muscles to induce ankle dorsiflexion motion, whereas the NMES group received NMES. The stimulus current was a biphasic waveform with a pulse duration of 200 μs and a frequency of 60 Hz. Patients in both groups underwent five 15 min sessions of electrical stimulation per week for three weeks. Indicators of motor function and ADL were measured pre- and posttreatment, including the Fugl-Meyer assessment of the lower extremity (FMA-LE) and modified Barthel index (MBI). Surface electromyography (sEMG) assessments included average electromyography (aEMG), integrated electromyography (iEMG), and root mean square (RMS) of the paretic TA muscle.

Results: Values for the FMA-LE, MBI, aEMG, iEMG, and RMS of the affected TA muscle were significantly increased in both groups after treatment (p < 0.01). Patients in the CCNMES group showed significant improvements in all the measurements compared with the NMES group after treatment. Within-group differences in all post- and pretreatment indicators were significantly greater in the CCNMES group than in the NMES group (p < 0.05).

Conclusion: CCNMES improved motor function and ADL ability to a greater extent than the conventional NMES in subacute stroke patients.

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一种新的对侧控制神经肌肉电刺激对恢复中风幸存者下肢运动能力和日常生活活动的有效性:一项随机对照试验。

背景:对侧控制神经肌肉电刺激(CCNMES)是一种新型的脑卒中电刺激治疗方法;然而，CCNMES对脑卒中后下肢功能的疗效报道很少。目的:比较CCNMES与NMES对亚急性脑卒中患者下肢功能和日常生活活动(ADL)的影响。方法:将44例有亚急性脑卒中病史的患者随机分为CCNMES组和NMES组(每组22例)。每组21名患者完成了每个方案的研究，每组有1名受试者失去随访。CCNMES组采用胫前肌(TA)、腓骨长肌和腓骨短肌施加CCNMES，诱导踝关节背屈运动，NMES组采用NMES。刺激电流为脉冲持续时间为200 μs、频率为60 Hz的双相波形。两组患者每周进行5次15分钟的电刺激，持续3周。治疗前后分别测量运动功能和ADL指标，包括Fugl-Meyer下肢评分(FMA-LE)和改良Barthel指数(MBI)。表面肌电图(sEMG)评估包括平均肌电图(aEMG)、综合肌电图(iEMG)和麻痹TA肌的均方根(RMS)。结果:两组患者治疗后TA肌FMA-LE、MBI、aEMG、iEMG及RMS值均显著升高(p < 0.01)。与NMES组相比，CCNMES组患者在治疗后的所有测量指标均有显著改善。CCNMES组治疗前后各项指标组内差异均显著大于NMES组(p < 0.05)。结论:CCNMES比常规NMES更能改善亚急性脑卒中患者的运动功能和日常生活能力。

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来源期刊

ACS Applied Electronic Materials Multiple-

CiteScore

7.20

自引率

4.30%

发文量

567

期刊介绍： ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/Abstracted： Web of Science SCIE Scopus CAS INSPEC Portico