Doing Great With DOTATATE: Update on GA-68 DOTATATE Positron Emission Tomography/Computed Tomography and Magnetic Resonance Imaging for Evaluation of Sinonasal Tumors.

Q2 Medicine

Topics in Magnetic Resonance Imaging Pub Date : 2021-06-01 DOI:10.1097/RMR.0000000000000289

Avraham B Zlochower, Jared M Steinklein

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引用次数: 2

Abstract

Abstract: Sinonasal tumors are relatively rare and radiographically challenging to evaluate due to their wide variety of pathologies and imaging features. However, sinonasal tumors possessing somatostatin receptor overexpression have the benefit of utilizing a multimodality anatomic and functional imaging for a more comprehensive evaluation. This is particularly evident with esthesioneuroblastoma, with computed tomography and magnetic resonance imaging defining the anatomic extent of the tumor, whereas somatostatin receptor imaging, particularly with gallium-68 DOTATATE positron emission tomography/computed tomography, is used to assess the presence of metastatic disease for staging purposes as well as in the surveillance for tumor recurrence. In addition, areas which accumulate gallium-68 DOTATATE are potentially amenable to treatment with peptide receptor radionuclide therapy. In this manner, a combined approach of anatomic and functional imaging is critical for optimal imaging evaluation and treatment strategy of patients with sinonasal tumors.

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用DOTATATE做得很好:GA-68 DOTATATE正电子发射断层扫描/计算机断层扫描和磁共振成像评估鼻窦肿瘤的最新进展。

摘要:鼻窦肿瘤相对罕见，由于其多种多样的病理和影像学特征，其影像学评估具有挑战性。然而，具有生长抑素受体过表达的鼻窦肿瘤可以利用多模态解剖和功能成像进行更全面的评估。这在神经母细胞瘤中尤其明显，计算机断层扫描和磁共振成像确定了肿瘤的解剖范围，而生长抑素受体成像，特别是镓-68 DOTATATE正电子发射断层扫描/计算机断层扫描，用于评估转移性疾病的存在，用于分期目的以及肿瘤复发的监测。此外，积累镓-68 DOTATATE的区域可能适用于肽受体放射性核素治疗。因此，解剖和功能成像的结合对于鼻窦肿瘤患者的最佳影像学评估和治疗策略至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Topics in Magnetic Resonance Imaging Medicine-Medicine (all)

CiteScore

5.50

自引率

0.00%

发文量

期刊介绍： Topics in Magnetic Resonance Imaging is a leading information resource for professionals in the MRI community. This publication supplies authoritative, up-to-the-minute coverage of technical advances in this evolving field as well as practical, hands-on guidance from leading experts. Six times a year, TMRI focuses on a single timely topic of interest to radiologists. These topical issues present a variety of perspectives from top radiological authorities to provide an in-depth understanding of how MRI is being used in each area.